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Estimating the Burden of Japanese Encephalitis Virus and Other Encephalitides in Countries of the Mekong Region

  • Arnaud Tarantola mail,

    atarantola@pasteur-kh.org

    Affiliation: Institut Pasteur du Cambodge, Phnom Penh, Cambodia

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  • Flavie Goutard,

    Affiliations: Institut Pasteur du Cambodge, Phnom Penh, Cambodia, Centre de coopération internationale en recherche agronomique pour le développement (CIRAD), Département ES, Unité AGIRs, Montpellier, France

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  • Paul Newton,

    Affiliation: Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Microbiology Laboratory, Mahosot Hospital, Vientiane, Lao PDR and Centre for Tropical Medicine, Nuffield Department of Medicine, Churchill Hospital, University of Oxford, Oxford, United Kingdom

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  • Xavier de Lamballerie,

    Affiliation: Aix Marseille University, IRD French Institute of Research for Development, EHESP French School of Public Health, UMR_D 190 “Emergence des Pathologies Virales”, Marseille, France

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  • Olivier Lortholary,

    Affiliation: Université René Descartes, Hôpital Necker-Enfants malades, Centre d'Infectiologie Necker Pasteur, IHU Imagine, Labex IBEID, Paris, France

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  • Julien Cappelle,

    Affiliations: Institut Pasteur du Cambodge, Phnom Penh, Cambodia, Centre de coopération internationale en recherche agronomique pour le développement (CIRAD), Département ES, Unité AGIRs, Montpellier, France

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  • Philippe Buchy

    Affiliation: Institut Pasteur du Cambodge, Phnom Penh, Cambodia

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  • Published: January 30, 2014
  • DOI: 10.1371/journal.pntd.0002533

Reader Comments (1)

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few comments and urge to a global approach with JEV as a case study

Posted by SISEA-MRC on 01 Feb 2014 at 07:20 GMT

Dear Arnaud and Al.
Firstly, congratulations for this preliminary and necessary review of literature concerning a major public health concern in SEA region. I would like to provide few comments in 6 bullet points:
1. Myanmar is definitely part of the Mekong Sub-region, including at the political level (Mekong River Sub-region at ASEAN, MBDS for disease surveillance). Due to the size (surface and population) of this country, and due to its expected very fast development in all sectors, including agricuture and transport, its impact on the change of epidemiological patterns of communicable diseases is to be taken into consideration, including for JEV and other encephalitis,
2. Quality of primary health care: this is how to improve surveillance, case management and disease control. I believe it is the right level of analysis and action (district/commune),
3. Animal health wise: it is not just JEV vaccination, but also pig raising methods and integration with rice culture,
4. Grey literature from the numerous regional meeting tackling JEV (for instance the last WPRO meeting on vaccination, held in Manila in 2013) should be included in this kind of assessment,
5. Change in demographics and in economic trends as well as in agriculture and urban settings’ relations will lead to a change in the epidemiological setting of JEV, with a probable shift to occasional urban outbreaks,
6. The only way of improvement is a more global approach estimating how to put together as a unique strategy of control: human and animal, vaccine and case management, agriculture sector and public health. Global health are not just words, but definitely the right vision that encompasses all aspects of health as a component of sustainable development for all.

Again, thank you very much for this great job at IPC!.

JJ Bernatas

No competing interests declared.