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Research Article

Transcriptional Changes in the Hookworm, Ancylostoma caninum, during the Transition from a Free-Living to a Parasitic Larva

  • Bennett J. D. Datu,

    Affiliations: Helminth Biology Laboratory, Division of Infectious Diseases and Immunology, Queensland Institute of Medical Research, Herston, Queensland, Australia, School of Molecular and Microbial Sciences, The University of Queensland, Brisbane, Australia

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  • Robin B. Gasser mail,

    ROBINBG@unimelb.edu.au (RG); Alex.Loukas@qimr.edu.au (AL)

    Affiliation: Department of Veterinary Science, The University of Melbourne, Werribee, Victoria, Australia

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  • Shivashankar H. Nagaraj,

    Affiliation: Department of Chemistry and Biomolecular Sciences & Biotechnology Research Institute, Macquarie University, Sydney, New South Wales, Australia

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  • Eng K. Ong,

    Affiliation: Department of Science, Museum Victoria, Melbourne, Victoria, Australia

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  • Peter O'Donoghue,

    Affiliation: School of Molecular and Microbial Sciences, The University of Queensland, Brisbane, Australia

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  • Russell McInnes,

    Affiliation: Agilent Technologies, Forest Hill, Victoria, Australia

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  • Shoba Ranganathan,

    Affiliation: Department of Chemistry and Biomolecular Sciences & Biotechnology Research Institute, Macquarie University, Sydney, New South Wales, Australia

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  • Alex Loukas mail

    ROBINBG@unimelb.edu.au (RG); Alex.Loukas@qimr.edu.au (AL)

    Affiliation: Helminth Biology Laboratory, Division of Infectious Diseases and Immunology, Queensland Institute of Medical Research, Herston, Queensland, Australia

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  • Published: January 09, 2008
  • DOI: 10.1371/journal.pntd.0000130

About the Authors

Bennett J. D. Datu, Alex Loukas
Helminth Biology Laboratory, Division of Infectious Diseases and Immunology, Queensland Institute of Medical Research, Herston, Queensland, Australia
Bennett J. D. Datu, Peter O'Donoghue
School of Molecular and Microbial Sciences, The University of Queensland, Brisbane, Australia
Robin B. Gasser
Department of Veterinary Science, The University of Melbourne, Werribee, Victoria, Australia
Shivashankar H. Nagaraj, Shoba Ranganathan
Department of Chemistry and Biomolecular Sciences & Biotechnology Research Institute, Macquarie University, Sydney, New South Wales, Australia
Eng K. Ong
Department of Science, Museum Victoria, Melbourne, Victoria, Australia
Russell McInnes
Agilent Technologies, Forest Hill, Victoria, Australia

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: RG AL BD. Performed the experiments: BD. Analyzed the data: SN BD EO. Contributed reagents/materials/analysis tools: SR SN EO PO RM. Wrote the paper: RG AL BD.