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Research Article

Killing of Trypanosomatid Parasites by a Modified Bovine Host Defense Peptide, BMAP-18

  • Lee R. Haines,

    Affiliation: Department of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia, Canada

    Current address: Liverpool School of Tropical Medicine, Liverpool, United Kingdom

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  • Jamie M. Thomas,

    Affiliation: Department of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia, Canada

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  • Angela M. Jackson,

    Affiliation: Department of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia, Canada

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  • Brett A. Eyford,

    Affiliation: Department of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia, Canada

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  • Morteza Razavi,

    Affiliation: Department of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia, Canada

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  • Cristalle N. Watson,

    Affiliation: Department of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia, Canada

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  • Brent Gowen,

    Affiliation: Department of Biology, University of Victoria, Victoria, British Columbia, Canada

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  • Robert E. W. Hancock,

    Affiliation: Department of Microbiology and Immunology, University of British Columbia, Vancouver, British Columbia, Canada

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  • Terry W. Pearson mail

    parasite@uvic.ca

    Affiliation: Department of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia, Canada

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  • Published: February 03, 2009
  • DOI: 10.1371/journal.pntd.0000373

About the Authors

Lee R. Haines, Jamie M. Thomas, Angela M. Jackson, Brett A. Eyford, Morteza Razavi, Cristalle N. Watson, Terry W. Pearson
Department of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia, Canada
Brent Gowen
Department of Biology, University of Victoria, Victoria, British Columbia, Canada
Robert E. W. Hancock
Department of Microbiology and Immunology, University of British Columbia, Vancouver, British Columbia, Canada

Corresponding Author

Email: parasite@uvic.ca

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: LRH TWP. Performed the experiments: LRH JMT AMJ BAE MR CNW BG. Analyzed the data: LRH JMT AMJ BAE MR TWP. Contributed reagents/materials/analysis tools: BG REWH TWP. Wrote the paper: LRH JMT REWH TWP.