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Research Article

Functional Analysis of the Cathepsin-Like Cysteine Protease Genes in Adult Brugia malayi Using RNA Interference

  • Louise Ford mail,

    louise.ford@liverpool.ac.uk

    Affiliation: Laboratory of Molecular Parasitology, Lindsley F. Kimball Research Institute, New York Blood Center, New York, New York, United States of America

    Current address: Filariasis Research Group, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, United Kingdom

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  • Jun Zhang,

    Affiliation: Laboratory of Molecular Parasitology, Lindsley F. Kimball Research Institute, New York Blood Center, New York, New York, United States of America

    Current address: Laboratory of Developmental Biology, Lindsley F. Kimball Research Institute, New York Blood Center, New York, New York, United States of America

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  • Jing Liu,

    Affiliation: Laboratory of Molecular Parasitology, Lindsley F. Kimball Research Institute, New York Blood Center, New York, New York, United States of America

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  • Sarwar Hashmi,

    Affiliation: Laboratory of Molecular Parasitology, Lindsley F. Kimball Research Institute, New York Blood Center, New York, New York, United States of America

    Current address: Laboratory of Developmental Biology, Lindsley F. Kimball Research Institute, New York Blood Center, New York, New York, United States of America

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  • Juliet A. Fuhrman,

    Affiliation: Department of Biology, Tufts University, Medford, Massachusetts, United States of America

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  • Yelena Oksov,

    Affiliation: Laboratory of Electron Microscopy, Lindsley F. Kimball Research Institute, New York Blood Center, New York, New York, United States of America

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  • Sara Lustigman

    Affiliation: Laboratory of Molecular Parasitology, Lindsley F. Kimball Research Institute, New York Blood Center, New York, New York, United States of America

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  • Published: February 10, 2009
  • DOI: 10.1371/journal.pntd.0000377

About the Authors

Louise Ford, Jun Zhang, Jing Liu, Sarwar Hashmi, Sara Lustigman
Laboratory of Molecular Parasitology, Lindsley F. Kimball Research Institute, New York Blood Center, New York, New York, United States of America
Juliet A. Fuhrman
Department of Biology, Tufts University, Medford, Massachusetts, United States of America
Yelena Oksov
Laboratory of Electron Microscopy, Lindsley F. Kimball Research Institute, New York Blood Center, New York, New York, United States of America

Corresponding Author

Email: louise.ford@liverpool.ac.uk

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: LF SH SL. Performed the experiments: LF JZ JL SH JAF YO. Analyzed the data: LF SL. Contributed reagents/materials/analysis tools: SL. Wrote the paper: LF SL.