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Fatal Human Rabies due to Duvenhage Virus from a Bat in Kenya: Failure of Treatment with Coma-Induction, Ketamine, and Antiviral Drugs

  • Pieter-Paul A. M. van Thiel mail,

    p.p.vanthiel@amc.uva.nl

    Affiliation: Department of Infectious Diseases, Tropical Medicine and AIDS, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

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  • Rob M. A. de Bie,

    Affiliation: Department of Neurology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

    X
  • Filip Eftimov,

    Affiliation: Department of Neurology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

    X
  • Robert Tepaske,

    Affiliation: Department of Intensive Care, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

    X
  • Hans L. Zaaijer,

    Affiliation: Department of Clinical Virology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

    X
  • Gerard J. J. van Doornum,

    Affiliation: Department of Virology, Erasmus Medical Centre, Rotterdam, The Netherlands

    X
  • Martin Schutten,

    Affiliation: Department of Virology, Erasmus Medical Centre, Rotterdam, The Netherlands

    X
  • Albert D. M. E. Osterhaus,

    Affiliation: Department of Virology, Erasmus Medical Centre, Rotterdam, The Netherlands

    X
  • Charles B. L. M. Majoie,

    Affiliation: Department of Radiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

    X
  • Eleonora Aronica,

    Affiliation: Department of Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

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  • Christine Fehlner-Gardiner,

    Affiliation: Centre of Expertise for Rabies, Canadian Food Inspection Agency, Ottawa Laboratory (Fallowfield), Ottawa, Ontario, Canada

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  • Alex I. Wandeler,

    Affiliation: Centre of Expertise for Rabies, Canadian Food Inspection Agency, Ottawa Laboratory (Fallowfield), Ottawa, Ontario, Canada

    X
  • Piet A. Kager

    Affiliation: Department of Infectious Diseases, Tropical Medicine and AIDS, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

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  • Published: July 28, 2009
  • DOI: 10.1371/journal.pntd.0000428

About the Authors

Pieter-Paul A. M. van Thiel, Piet A. Kager
Department of Infectious Diseases, Tropical Medicine and AIDS, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Rob M. A. de Bie, Filip Eftimov
Department of Neurology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Robert Tepaske
Department of Intensive Care, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Hans L. Zaaijer
Department of Clinical Virology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Gerard J. J. van Doornum, Martin Schutten, Albert D. M. E. Osterhaus
Department of Virology, Erasmus Medical Centre, Rotterdam, The Netherlands
Charles B. L. M. Majoie
Department of Radiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Eleonora Aronica
Department of Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Christine Fehlner-Gardiner, Alex I. Wandeler
Centre of Expertise for Rabies, Canadian Food Inspection Agency, Ottawa Laboratory (Fallowfield), Ottawa, Ontario, Canada

Corresponding Author

Email: p.p.vanthiel@amc.uva.nl

Competing Interests

The authors have declared that no competing interests exist.