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Research Article

Soluble ST2 Levels Are Associated with Bleeding in Patients with Severe Leptospirosis

  • Jiri F. P. Wagenaar mail,

    jfpwagenaar@hotmail.com

    Affiliation: Department of Internal Medicine, Slotervaart Hospital, Amsterdam, The Netherlands

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  • M. Hussein Gasem,

    Affiliation: Department of Internal Medicine, Dr. Kariadi Hospital–Diponegoro University, Semarang, Indonesia

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  • Marga G. A. Goris,

    Affiliation: Royal Tropical Institute (KIT), KIT Biomedical Research, Amsterdam, The Netherlands

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  • Mariska Leeflang,

    Affiliation: Royal Tropical Institute (KIT), KIT Biomedical Research, Amsterdam, The Netherlands

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  • Rudy A. Hartskeerl,

    Affiliation: Royal Tropical Institute (KIT), KIT Biomedical Research, Amsterdam, The Netherlands

    X
  • Tom van der Poll,

    Affiliation: Center for Experimental and Molecular Medicine, Amsterdam, The Netherlands

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  • Cornelis van 't Veer,

    Affiliation: Center for Experimental and Molecular Medicine, Amsterdam, The Netherlands

    X
  • Eric C. M. van Gorp

    Affiliation: Department of Internal Medicine, Slotervaart Hospital, Amsterdam, The Netherlands

    X
  • Published: June 02, 2009
  • DOI: 10.1371/journal.pntd.0000453

About the Authors

Jiri F. P. Wagenaar, Eric C. M. van Gorp
Department of Internal Medicine, Slotervaart Hospital, Amsterdam, The Netherlands
M. Hussein Gasem
Department of Internal Medicine, Dr. Kariadi Hospital–Diponegoro University, Semarang, Indonesia
Marga G. A. Goris, Mariska Leeflang, Rudy A. Hartskeerl
Royal Tropical Institute (KIT), KIT Biomedical Research, Amsterdam, The Netherlands
Tom van der Poll, Cornelis van 't Veer
Center for Experimental and Molecular Medicine, Amsterdam, The Netherlands

Corresponding Author

Email: jfpwagenaar@hotmail.com

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JFPW MHG MGAG RAH TvdP CvV ECMvG. Performed the experiments: JFPW MGAG. Analyzed the data: JFPW MHG ML RAH TvdP CvV ECMvG. Contributed reagents/materials/analysis tools: MGAG TvdP CvV. Wrote the paper: JFPW.