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Research Article

The Liver Plays a Major Role in Clearance and Destruction of Blood Trypomastigotes in Trypanosoma cruzi Chronically Infected Mice

  • Luiz Roberto Sardinha mail,

    luizsard@usp.br

    Affiliation: Department of Immunology, Biomedical Sciences Institute, University of São Paulo, São Paulo, São Paulo, Brazil

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  • Tainá Mosca,

    Affiliation: Department of Immunology, Biomedical Sciences Institute, University of São Paulo, São Paulo, São Paulo, Brazil

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  • Rosa Maria Elias,

    Affiliation: Department of Immunology, Biomedical Sciences Institute, University of São Paulo, São Paulo, São Paulo, Brazil

    X
  • Rogério Silva do Nascimento,

    Affiliation: Department of Immunology, Biomedical Sciences Institute, University of São Paulo, São Paulo, São Paulo, Brazil

    X
  • Lígia A. Gonçalves,

    Affiliation: Instituto Gulbenkian de Ciência, Oeiras, Portugal

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  • Daniella Zanetti Bucci,

    Affiliation: Department of Immunology, Biomedical Sciences Institute, University of São Paulo, São Paulo, São Paulo, Brazil

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  • Cláudio Romero Farias Marinho,

    Affiliations: Department of Immunology, Biomedical Sciences Institute, University of São Paulo, São Paulo, São Paulo, Brazil, Department of Parasitology, Biomedical Sciences Institute, University of São Paulo, São Paulo, São Paulo, Brazil

    X
  • Carlos Penha-Gonçalves,

    Affiliation: Instituto Gulbenkian de Ciência, Oeiras, Portugal

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  • Maria Regina D'Império Lima,

    Affiliation: Department of Immunology, Biomedical Sciences Institute, University of São Paulo, São Paulo, São Paulo, Brazil

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  • José Maria Álvarez

    Affiliation: Department of Immunology, Biomedical Sciences Institute, University of São Paulo, São Paulo, São Paulo, Brazil

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  • Published: January 05, 2010
  • DOI: 10.1371/journal.pntd.0000578

About the Authors

Luiz Roberto Sardinha, Tainá Mosca, Rosa Maria Elias, Rogério Silva do Nascimento, Daniella Zanetti Bucci, Cláudio Romero Farias Marinho, Maria Regina D'Império Lima, José Maria Álvarez
Department of Immunology, Biomedical Sciences Institute, University of São Paulo, São Paulo, São Paulo, Brazil
Lígia A. Gonçalves, Carlos Penha-Gonçalves
Instituto Gulbenkian de Ciência, Oeiras, Portugal
Cláudio Romero Farias Marinho
Department of Parasitology, Biomedical Sciences Institute, University of São Paulo, São Paulo, São Paulo, Brazil

Corresponding Author

Email: luizsard@usp.br

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: LRS TM RME RSdN LAG CRFM CPG MRDL JM. Performed the experiments: LRS TM RME RSdN LAG DZB CRFM. Analyzed the data: LRS RSdN LAG DZB CRFM CPG MRDL JM. Contributed reagents/materials/analysis tools: CPG MRDL JM. Wrote the paper: LRS MRDL JM.