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Research Article

Schistosoma mansoni Stomatin Like Protein-2 Is Located in the Tegument and Induces Partial Protection against Challenge Infection

  • Leonardo P. Farias,

    Affiliation: Centro de Biotecnologia, Instituto Butantan, São Paulo, SP, Brazil

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  • Fernanda C. Cardoso,

    Affiliation: Departmento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil

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  • Patricia A. Miyasato,

    Affiliation: Centro de Biotecnologia, Instituto Butantan, São Paulo, SP, Brazil

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  • Bogar O. Montoya,

    Affiliation: Centro de Biotecnologia, Instituto Butantan, São Paulo, SP, Brazil

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  • Cibele A. Tararam,

    Affiliation: Centro de Biotecnologia, Instituto Butantan, São Paulo, SP, Brazil

    X
  • Henrique K. Roffato,

    Affiliation: Centro de Biotecnologia, Instituto Butantan, São Paulo, SP, Brazil

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  • Toshie Kawano,

    Affiliation: Centro de Biotecnologia, Instituto Butantan, São Paulo, SP, Brazil

    X
  • Andrea Gazzinelli,

    Affiliation: Escola de Enfermagem, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil

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  • Rodrigo Correa-Oliveira,

    Affiliation: Laboratório de Imunologia e Biologia Molecular, Centro de Pesquisas René Rachou (CPqRR), Fiocruz, Belo Horizonte, MG, Brazil

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  • Patricia S. Coulson,

    Affiliation: Department of Biology, University of York, York, United Kingdom

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  • R. Alan Wilson,

    Affiliation: Department of Biology, University of York, York, United Kingdom

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  • Sérgio C. Oliveira,

    Affiliation: Departmento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil

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  • Luciana C. C. Leite mail

    lccleite@butantan.gov.br

    Affiliation: Centro de Biotecnologia, Instituto Butantan, São Paulo, SP, Brazil

    X
  • Published: February 09, 2010
  • DOI: 10.1371/journal.pntd.0000597

About the Authors

Leonardo P. Farias, Patricia A. Miyasato, Bogar O. Montoya, Cibele A. Tararam, Henrique K. Roffato, Toshie Kawano, Luciana C. C. Leite
Centro de Biotecnologia, Instituto Butantan, São Paulo, SP, Brazil
Fernanda C. Cardoso, Sérgio C. Oliveira
Departmento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil
Andrea Gazzinelli
Escola de Enfermagem, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil
Rodrigo Correa-Oliveira
Laboratório de Imunologia e Biologia Molecular, Centro de Pesquisas René Rachou (CPqRR), Fiocruz, Belo Horizonte, MG, Brazil
Patricia S. Coulson, R. Alan Wilson
Department of Biology, University of York, York, United Kingdom

Corresponding Author

Email: lccleite@butantan.gov.br

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: LPF FCC TK RCO PSC RAW SCO LCCL. Performed the experiments: LPF FCC PAM BOM CAT PSC. Analyzed the data: LPF FCC PAM BOM CAT HKR TK AG RCO PSC RAW SCO LCCL. Contributed reagents/materials/analysis tools: AG RCO RAW SCO LCCL. Wrote the paper: LPF FCC RAW SCO LCCL.