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Research Article

Expression and Function of Macrophage Migration Inhibitory Factor (MIF) in Melioidosis

  • W. Joost Wiersinga mail,

    w.j.wiersinga@amc.uva.nl

    Affiliations: Center for Infection and Immunity Amsterdam (CINIMA), Academic Medical Center, Amsterdam, The Netherlands, Center for Experimental and Molecular Medicine (CEMM), Academic Medical Center, Amsterdam, The Netherlands

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  • Thierry Calandra,

    Affiliation: Infectious Diseases Service, Department of Medicine, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland

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  • Liesbeth M. Kager,

    Affiliations: Center for Infection and Immunity Amsterdam (CINIMA), Academic Medical Center, Amsterdam, The Netherlands, Center for Experimental and Molecular Medicine (CEMM), Academic Medical Center, Amsterdam, The Netherlands

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  • Gerritje J. W. van der Windt,

    Affiliations: Center for Infection and Immunity Amsterdam (CINIMA), Academic Medical Center, Amsterdam, The Netherlands, Center for Experimental and Molecular Medicine (CEMM), Academic Medical Center, Amsterdam, The Netherlands

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  • Thierry Roger,

    Affiliation: Infectious Diseases Service, Department of Medicine, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland

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  • Didier le Roy,

    Affiliation: Infectious Diseases Service, Department of Medicine, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland

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  • Sandrine Florquin,

    Affiliation: Department of Pathology, Academic Medical Center, Amsterdam, The Netherlands

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  • Sharon J. Peacock,

    Affiliations: Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand, Center for Clinical Vaccinology and Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom

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  • Fred C. G. J. Sweep,

    Affiliation: Chemical Endocrinology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands

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  • Tom van der Poll

    Affiliations: Center for Infection and Immunity Amsterdam (CINIMA), Academic Medical Center, Amsterdam, The Netherlands, Center for Experimental and Molecular Medicine (CEMM), Academic Medical Center, Amsterdam, The Netherlands

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  • Published: February 16, 2010
  • DOI: 10.1371/journal.pntd.0000605

About the Authors

W. Joost Wiersinga, Liesbeth M. Kager, Gerritje J. W. van der Windt, Tom van der Poll
Center for Infection and Immunity Amsterdam (CINIMA), Academic Medical Center, Amsterdam, The Netherlands
W. Joost Wiersinga, Liesbeth M. Kager, Gerritje J. W. van der Windt, Tom van der Poll
Center for Experimental and Molecular Medicine (CEMM), Academic Medical Center, Amsterdam, The Netherlands
Thierry Calandra, Thierry Roger, Didier le Roy
Infectious Diseases Service, Department of Medicine, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland
Sandrine Florquin
Department of Pathology, Academic Medical Center, Amsterdam, The Netherlands
Sharon J. Peacock
Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
Sharon J. Peacock
Center for Clinical Vaccinology and Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom
Fred C. G. J. Sweep
Chemical Endocrinology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands

Corresponding Author

Email: w.j.wiersinga@amc.uva.nl

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: WJW TC TR DlR SJP TvdP. Performed the experiments: WJW LMK GJWvdW FCGJS. Analyzed the data: WJW TC LMK GJWvdW SF SJP FCGJS TvdP. Contributed reagents/materials/analysis tools: WJW TC TR DlR SF SJP FCGJS TvdP. Wrote the paper: WJW TC SJP FCGJS TvdP.