Advertisement
Research Article

Antileishmanial High-Throughput Drug Screening Reveals Drug Candidates with New Scaffolds

  • Jair L. Siqueira-Neto equal contributor,

    equal contributor Contributed equally to this work with: Jair L. Siqueira-Neto, Ok-Ryul Song, Hyunrim Oh

    Affiliation: Center for Neglected Diseases Drug Discovery (CND3), Institut Pasteur Korea, Seongnam-si, Gyeonggi-do, South Korea

    X
  • Ok-Ryul Song equal contributor,

    equal contributor Contributed equally to this work with: Jair L. Siqueira-Neto, Ok-Ryul Song, Hyunrim Oh

    Affiliation: Screening Technology & Pharmacology Group, Institut Pasteur Korea, Seongnam-si, Gyeonggi-do, South Korea

    X
  • Hyunrim Oh equal contributor,

    equal contributor Contributed equally to this work with: Jair L. Siqueira-Neto, Ok-Ryul Song, Hyunrim Oh

    Affiliation: Screening Technology & Pharmacology Group, Institut Pasteur Korea, Seongnam-si, Gyeonggi-do, South Korea

    X
  • Jeong-Hun Sohn,

    Affiliation: Active Compound Space Group, Institut Pasteur Korea, Seongnam-si, Gyeonggi-do, South Korea

    X
  • Gyongseon Yang,

    Affiliation: Center for Neglected Diseases Drug Discovery (CND3), Institut Pasteur Korea, Seongnam-si, Gyeonggi-do, South Korea

    X
  • Jiyoun Nam,

    Affiliation: Screening Technology & Pharmacology Group, Institut Pasteur Korea, Seongnam-si, Gyeonggi-do, South Korea

    X
  • Jiyeon Jang,

    Affiliation: Screening Technology & Pharmacology Group, Institut Pasteur Korea, Seongnam-si, Gyeonggi-do, South Korea

    X
  • Jonathan Cechetto,

    Affiliation: Screening Technology & Pharmacology Group, Institut Pasteur Korea, Seongnam-si, Gyeonggi-do, South Korea

    X
  • Chang Bok Lee,

    Affiliation: Screening Technology & Pharmacology Group, Institut Pasteur Korea, Seongnam-si, Gyeonggi-do, South Korea

    X
  • Seunghyun Moon,

    Affiliation: Image Mining Group, Institut Pasteur Korea, Seongnam-si, Gyeonggi-do, South Korea

    X
  • Auguste Genovesio,

    Affiliation: Image Mining Group, Institut Pasteur Korea, Seongnam-si, Gyeonggi-do, South Korea

    X
  • Eric Chatelain,

    Affiliation: Drugs for Neglected Diseases initiative (DNDi), Geneva, Switzerland

    X
  • Thierry Christophe,

    Affiliation: Screening Technology & Pharmacology Group, Institut Pasteur Korea, Seongnam-si, Gyeonggi-do, South Korea

    X
  • Lucio H. Freitas-Junior mail

    freitasjunior@ip-korea.org

    Affiliation: Center for Neglected Diseases Drug Discovery (CND3), Institut Pasteur Korea, Seongnam-si, Gyeonggi-do, South Korea

    X
  • Published: May 04, 2010
  • DOI: 10.1371/journal.pntd.0000675

About the Authors

Jair L. Siqueira-Neto, Gyongseon Yang, Lucio H. Freitas-Junior
Center for Neglected Diseases Drug Discovery (CND3), Institut Pasteur Korea, Seongnam-si, Gyeonggi-do, South Korea
Ok-Ryul Song, Hyunrim Oh, Jiyoun Nam, Jiyeon Jang, Jonathan Cechetto, Chang Bok Lee, Thierry Christophe
Screening Technology & Pharmacology Group, Institut Pasteur Korea, Seongnam-si, Gyeonggi-do, South Korea
Jeong-Hun Sohn
Active Compound Space Group, Institut Pasteur Korea, Seongnam-si, Gyeonggi-do, South Korea
Seunghyun Moon, Auguste Genovesio
Image Mining Group, Institut Pasteur Korea, Seongnam-si, Gyeonggi-do, South Korea
Eric Chatelain
Drugs for Neglected Diseases initiative (DNDi), Geneva, Switzerland

Corresponding Author

Email: freitasjunior@ip-korea.org

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JLSN GY TC LHFJ. Performed the experiments: JLSN ORS HO JN JJ. Analyzed the data: JLSN ORS HO JHS JC TC LHFJ. Contributed reagents/materials/analysis tools: CBL SM AG LHFJ. Wrote the paper: JLSN JHS GY JC EC LHFJ.