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Research Article

Immunostimulatory Properties of Dendritic Cells after Leishmania donovani Infection Using an In Vitro Model of Liver Microenvironment

  • Ludovic Donaghy equal contributor,

    equal contributor Contributed equally to this work with: Ludovic Donaghy, Florian Cabillic

    Affiliations: Université de Rennes 1, Rennes, France, Inserm U522, Régulation des Equilibres Fonctionnels du Foie Normal et Pathologique, Rennes, France

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  • Florian Cabillic equal contributor,

    equal contributor Contributed equally to this work with: Ludovic Donaghy, Florian Cabillic

    Affiliations: Université de Rennes 1, Rennes, France, EE 341 Biothérapies Innovantes, Rennes, France, Laboratoire de Cytogénétique et Biologie Cellulaire, CHU Rennes, Rennes, France

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  • Anne Corlu,

    Affiliations: Université de Rennes 1, Rennes, France, Inserm, UMR991, Liver Metabolisms and Cancer, Rennes, France

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  • Octavie Rostan,

    Affiliations: Université de Rennes 1, Rennes, France, EA SeRAIC 4427, IRSET, Rennes, France

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  • Olivier Toutirais,

    Affiliations: Université de Rennes 1, Rennes, France, EE 341 Biothérapies Innovantes, Rennes, France

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  • Christiane Guguen-Guillouzo,

    Affiliations: Université de Rennes 1, Rennes, France, Inserm, UMR991, Liver Metabolisms and Cancer, Rennes, France

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  • Claude Guiguen,

    Affiliations: Université de Rennes 1, Rennes, France, Laboratoire de Parasitologie-Mycologie, CHU Rennes, Rennes, France

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  • Jean-Pierre Gangneux mail

    jean-pierre.gangneux@univ-rennes1.fr

    Affiliations: Université de Rennes 1, Rennes, France, EA SeRAIC 4427, IRSET, Rennes, France, Laboratoire de Parasitologie-Mycologie, CHU Rennes, Rennes, France

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  • Published: June 08, 2010
  • DOI: 10.1371/journal.pntd.0000703

About the Authors

Ludovic Donaghy, Florian Cabillic, Anne Corlu, Octavie Rostan, Olivier Toutirais, Christiane Guguen-Guillouzo, Claude Guiguen, Jean-Pierre Gangneux
Université de Rennes 1, Rennes, France
Ludovic Donaghy
Inserm U522, Régulation des Equilibres Fonctionnels du Foie Normal et Pathologique, Rennes, France
Florian Cabillic, Olivier Toutirais
EE 341 Biothérapies Innovantes, Rennes, France
Florian Cabillic
Laboratoire de Cytogénétique et Biologie Cellulaire, CHU Rennes, Rennes, France
Anne Corlu, Christiane Guguen-Guillouzo
Inserm, UMR991, Liver Metabolisms and Cancer, Rennes, France
Octavie Rostan, Jean-Pierre Gangneux
EA SeRAIC 4427, IRSET, Rennes, France
Claude Guiguen, Jean-Pierre Gangneux
Laboratoire de Parasitologie-Mycologie, CHU Rennes, Rennes, France

Corresponding Author

Email: jean-pierre.gangneux@univ-rennes1.fr

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: LD FC AC CGG CG JPG. Performed the experiments: LD FC AC OR OT JPG. Analyzed the data: LD FC AC CGG CG JPG. Contributed reagents/materials/analysis tools: LD FC AC JPG. Wrote the paper: LD FC AC CGG CG JPG.