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Research Article

Gene Expression Patterns of Dengue Virus-Infected Children from Nicaragua Reveal a Distinct Signature of Increased Metabolism

  • P'ng Loke mail,

    png.loke@nyumc.org (PL); eharris@berkeley.edu (EH)

    Affiliation: Department of Medical Parasitology, School of Medicine, New York University, New York, New York, United States of America

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  • Samantha N. Hammond,

    Affiliation: Sustainable Sciences Institute, Managua, Nicaragua

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  • Jacqueline M. Leung,

    Affiliation: Department of Medical Parasitology, School of Medicine, New York University, New York, New York, United States of America

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  • Charles C. Kim,

    Affiliation: Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, California, United States of America

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  • Sajeev Batra,

    Affiliation: Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, California, United States of America

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  • Crisanta Rocha,

    Affiliation: Unidad de Infectología, Hospital Infantil Manuel Jesús de Rivera, Managua, Nicaragua

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  • Angel Balmaseda,

    Affiliation: Departamento de Virología, Centro Nacional de Diagóstico y Referencia, Ministerio de Salud, Managua, Nicaragua

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  • Eva Harris mail

    png.loke@nyumc.org (PL); eharris@berkeley.edu (EH)

    Affiliation: Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, California, United States of America

    X
  • Published: June 15, 2010
  • DOI: 10.1371/journal.pntd.0000710

About the Authors

P'ng Loke, Jacqueline M. Leung
Department of Medical Parasitology, School of Medicine, New York University, New York, New York, United States of America
Samantha N. Hammond
Sustainable Sciences Institute, Managua, Nicaragua
Charles C. Kim, Sajeev Batra
Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, California, United States of America
Crisanta Rocha
Unidad de Infectología, Hospital Infantil Manuel Jesús de Rivera, Managua, Nicaragua
Angel Balmaseda
Departamento de Virología, Centro Nacional de Diagóstico y Referencia, Ministerio de Salud, Managua, Nicaragua
Eva Harris
Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, California, United States of America

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: PL SNH EH. Performed the experiments: PL SNH JML. Analyzed the data: PL JML CCK SB EH. Contributed reagents/materials/analysis tools: PL SNH CR AB. Wrote the paper: PL EH.