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Research Article

Response to Treatment in a Prospective Cohort of Patients with Large Ulcerated Lesions Suspected to Be Buruli Ulcer (Mycobacterium ulcerans Disease)

  • Kapay Kibadi,

    Affiliations: Programme National de Lutte contre l'Ulcère de Buruli (PNLUB), Kinshasa, Democratic Republic of the Congo, Institut National de Recherche Biomédicale, Kinshasa, Democratic Republic of the Congo, Department of Surgery, University of Kinshasa, Kinshasa, Democratic Republic of the Congo

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  • Marleen Boelaert,

    Affiliation: Epidemiology Unit, Institute of Tropical Medicine, Antwerp, Belgium

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  • Alexandra G. Fraga,

    Affiliation: Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, Portugal

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  • Makanzu Kayinua,

    Affiliations: General Reference Hospital of Nsona-Mpangu, Lower-Congo, Democratic Republic of the Congo, Rural Health Zone of Nsona-Mpangu, Lower-Congo, Democratic Republic of the Congo

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  • Adhemar Longatto-Filho,

    Affiliations: Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, Portugal, Laboratory of Medical Investigation (LIM) 14, Department of Pathology of Faculty of Medicine of São Paulo State University, São Paulo, Brazil

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  • Jean-Bedel Minuku,

    Affiliation: Rural Health Zone of Nsona-Mpangu, Lower-Congo, Democratic Republic of the Congo

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  • Jean-Baptiste Mputu-Yamba,

    Affiliation: Department of Surgery, University of Kinshasa, Kinshasa, Democratic Republic of the Congo

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  • Jean-Jacques Muyembe-Tamfum,

    Affiliation: Institut National de Recherche Biomédicale, Kinshasa, Democratic Republic of the Congo

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  • Jorge Pedrosa,

    Affiliation: Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, Portugal

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  • Jean-Jacques Roux,

    Affiliation: Anatomy Pathology Unit, Hospital of Chambéry, Association Pathologie Cytologie Développement, Chambéry, France

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  • Wayne M. Meyers,

    Affiliation: Armed Forces Institute of Pathology (AFIP), Washington, D.C., United States of America

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  • Françoise Portaels mail

    portaels@itg.be

    Affiliation: Mycobacteriology Unit, Institute of Tropical Medicine, Antwerp, Belgium

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  • Published: July 06, 2010
  • DOI: 10.1371/journal.pntd.0000736

About the Authors

Kapay Kibadi
Programme National de Lutte contre l'Ulcère de Buruli (PNLUB), Kinshasa, Democratic Republic of the Congo
Kapay Kibadi, Jean-Jacques Muyembe-Tamfum
Institut National de Recherche Biomédicale, Kinshasa, Democratic Republic of the Congo
Kapay Kibadi, Jean-Baptiste Mputu-Yamba
Department of Surgery, University of Kinshasa, Kinshasa, Democratic Republic of the Congo
Marleen Boelaert
Epidemiology Unit, Institute of Tropical Medicine, Antwerp, Belgium
Alexandra G. Fraga, Adhemar Longatto-Filho, Jorge Pedrosa
Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, Portugal
Makanzu Kayinua
General Reference Hospital of Nsona-Mpangu, Lower-Congo, Democratic Republic of the Congo
Makanzu Kayinua, Jean-Bedel Minuku
Rural Health Zone of Nsona-Mpangu, Lower-Congo, Democratic Republic of the Congo
Adhemar Longatto-Filho
Laboratory of Medical Investigation (LIM) 14, Department of Pathology of Faculty of Medicine of São Paulo State University, São Paulo, Brazil
Jean-Jacques Roux
Anatomy Pathology Unit, Hospital of Chambéry, Association Pathologie Cytologie Développement, Chambéry, France
Wayne M. Meyers
Armed Forces Institute of Pathology (AFIP), Washington, D.C., United States of America
Françoise Portaels
Mycobacteriology Unit, Institute of Tropical Medicine, Antwerp, Belgium

Corresponding Author

Email: portaels@itg.be

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: KK MB FP. Performed the experiments: KK AGF MK ALF JBM JBMY JJMT JJR WM. Analyzed the data: KK MB JP WM FP. Contributed reagents/materials/analysis tools: AGF ALF JJMT JJR. Wrote the paper: KK MB WM FP.