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Research Article

Evaluation of Chikungunya Diagnostic Assays: Differences in Sensitivity of Serology Assays in Two Independent Outbreaks

  • Grace Yap,

    Affiliation: Environmental Health Institute, National Environment Agency, Singapore, Singapore

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  • Kwoon-Yong Pok,

    Affiliation: Environmental Health Institute, National Environment Agency, Singapore, Singapore

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  • Yee-Ling Lai,

    Affiliation: Environmental Health Institute, National Environment Agency, Singapore, Singapore

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  • Hapuarachchige-Chanditha Hapuarachchi,

    Affiliation: Environmental Health Institute, National Environment Agency, Singapore, Singapore

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  • Angela Chow,

    Affiliation: Communicable Disease Centre, Tan Tock Seng Hospital, Singapore, Singapore

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  • Yee-Sin Leo,

    Affiliation: Communicable Disease Centre, Tan Tock Seng Hospital, Singapore, Singapore

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  • Li-Kiang Tan,

    Affiliation: Environmental Health Institute, National Environment Agency, Singapore, Singapore

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  • Lee-Ching Ng mail

    ng_lee_ching@nea.gov.sg

    Affiliation: Environmental Health Institute, National Environment Agency, Singapore, Singapore

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  • Published: July 20, 2010
  • DOI: 10.1371/journal.pntd.0000753

About the Authors

Grace Yap, Kwoon-Yong Pok, Yee-Ling Lai, Hapuarachchige-Chanditha Hapuarachchi, Li-Kiang Tan, Lee-Ching Ng
Environmental Health Institute, National Environment Agency, Singapore, Singapore
Angela Chow, Yee-Sin Leo
Communicable Disease Centre, Tan Tock Seng Hospital, Singapore, Singapore

Corresponding Author

Email: ng_lee_ching@nea.gov.sg

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: GY LCN. Performed the experiments: GY KYP YLL. Analyzed the data: GY YLL HCH LCN. Contributed reagents/materials/analysis tools: HCH LKT. Wrote the paper: GY. Conceptualized and coordinated the study: LCN. Prepared the manuscript: LCN. Coordinated sample collection from the hospital: AC YSL. Coordinated sample collection and diagnostics: LKT. Isolated the viruses: LKT.