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Research Article

Design, Development and Evaluation of rK28-Based Point-of-Care Tests for Improving Rapid Diagnosis of Visceral Leishmaniasis

  • Sowmya Pattabhi,

    Affiliation: Infectious Disease Research Institute, Seattle, Washington, United States of America

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  • Jacqueline Whittle,

    Affiliation: Infectious Disease Research Institute, Seattle, Washington, United States of America

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  • Raodoh Mohamath,

    Affiliation: Infectious Disease Research Institute, Seattle, Washington, United States of America

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  • Sayda El-Safi,

    Affiliation: Department of Microbiology and Parasitology, Faculty of Medicine, Khartoum University, Khartoum, Sudan

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  • Garner G. Moulton,

    Affiliation: Infectious Disease Research Institute, Seattle, Washington, United States of America

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  • Jeffrey A. Guderian,

    Affiliation: Infectious Disease Research Institute, Seattle, Washington, United States of America

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  • Danny Colombara,

    Affiliation: Department of Epidemiology, School of Public Health, University of Washington, Seattle, Washington, United States of America

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  • Asem O. Abdoon,

    Affiliation: Institute of Endemic Diseases, University of Khartoum, Khartoum, Sudan

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  • Maowia M. Mukhtar,

    Affiliation: Institute of Endemic Diseases, University of Khartoum, Khartoum, Sudan

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  • Dinesh Mondal,

    Affiliation: Laboratory Sciences Division, International Centre for Diarrhoeal Diseases Research, Dhaka, Bangladesh

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  • Javan Esfandiari,

    Affiliation: Chembio Diagnostic Systems, Inc., Medford, New York, United States of America

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  • Shailendra Kumar,

    Affiliation: Chembio Diagnostic Systems, Inc., Medford, New York, United States of America

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  • Peter Chun,

    Affiliation: Ease-Medtrend, Shanghai, People's Republic of China

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  • Steven G. Reed,

    Affiliation: Infectious Disease Research Institute, Seattle, Washington, United States of America

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  • Ajay Bhatia mail

    abhatia@idri.org

    Affiliation: Infectious Disease Research Institute, Seattle, Washington, United States of America

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  • Published: September 14, 2010
  • DOI: 10.1371/journal.pntd.0000822

About the Authors

Sowmya Pattabhi, Jacqueline Whittle, Raodoh Mohamath, Garner G. Moulton, Jeffrey A. Guderian, Steven G. Reed, Ajay Bhatia
Infectious Disease Research Institute, Seattle, Washington, United States of America
Sayda El-Safi
Department of Microbiology and Parasitology, Faculty of Medicine, Khartoum University, Khartoum, Sudan
Danny Colombara
Department of Epidemiology, School of Public Health, University of Washington, Seattle, Washington, United States of America
Asem O. Abdoon, Maowia M. Mukhtar
Institute of Endemic Diseases, University of Khartoum, Khartoum, Sudan
Dinesh Mondal
Laboratory Sciences Division, International Centre for Diarrhoeal Diseases Research, Dhaka, Bangladesh
Javan Esfandiari, Shailendra Kumar
Chembio Diagnostic Systems, Inc., Medford, New York, United States of America
Peter Chun
Ease-Medtrend, Shanghai, People's Republic of China

Corresponding Author

Email: abhatia@idri.org

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SP AB. Performed the experiments: SP JW RM GGM JAG DC AOA MMM DM JE SK PC AB. Analyzed the data: SP AB. Contributed reagents/materials/analysis tools: SP SES SGR AB. Wrote the paper: SP SGR AB. Manufactured K28 DPP: JE SK. Manufactured the K28 LF: PC.