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Research Article

Chemosensitization of Trypanosoma congolense Strains Resistant to Isometamidium Chloride by Tetracyclines and Enrofloxacin

  • Vincent Delespaux mail,

    vdelespaux@itg.be

    Affiliation: Animal Health Department, Institute of Tropical Medicine Antwerp, Antwerp, Belgium

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  • Hervé Sèna Vitouley,

    Affiliation: Centre International de Recherche – Développement sur l'Elevage en Zone Subhumide, Bobo-Dioulasso, Burkina Faso

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  • Tanguy Marcotty,

    Affiliation: Animal Health Department, Institute of Tropical Medicine Antwerp, Antwerp, Belgium

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  • Niko Speybroeck,

    Affiliation: Animal Health Department, Institute of Tropical Medicine Antwerp, Antwerp, Belgium

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  • Dirk Berkvens,

    Affiliation: Animal Health Department, Institute of Tropical Medicine Antwerp, Antwerp, Belgium

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  • Krisna Roy,

    Affiliation: Pathology and Parasitology Department, Faculty of Veterinary Medicine, Chittagong Veterinary and Animal Sciences University, Khulshi, Chittagong, Bangladesh

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  • Stanny Geerts,

    Affiliation: Animal Health Department, Institute of Tropical Medicine Antwerp, Antwerp, Belgium

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  • Peter Van den Bossche

    Affiliations: Animal Health Department, Institute of Tropical Medicine Antwerp, Antwerp, Belgium, Department of Veterinary Tropical Diseases, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa

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  • Published: September 28, 2010
  • DOI: 10.1371/journal.pntd.0000828

About the Authors

Vincent Delespaux, Tanguy Marcotty, Niko Speybroeck, Dirk Berkvens, Stanny Geerts, Peter Van den Bossche
Animal Health Department, Institute of Tropical Medicine Antwerp, Antwerp, Belgium
Hervé Sèna Vitouley
Centre International de Recherche – Développement sur l'Elevage en Zone Subhumide, Bobo-Dioulasso, Burkina Faso
Krisna Roy
Pathology and Parasitology Department, Faculty of Veterinary Medicine, Chittagong Veterinary and Animal Sciences University, Khulshi, Chittagong, Bangladesh
Peter Van den Bossche
Department of Veterinary Tropical Diseases, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa

Corresponding Author

Email: vdelespaux@itg.be

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: VD. Performed the experiments: VD HSV KR. Analyzed the data: VD TM NS DB. Contributed reagents/materials/analysis tools: VD SG PVdB. Wrote the paper: VD. Performed all the experiments on mice: VD. Performed the experiments on cattle and all PCR's: HSV. Participated in the redaction of the manuscript: HSV TM NS DB SG PVdB. Validated the statistical model: NS DB. Performed some experiments on mice: KR.