Advertisement
Research Article

LXR Deficiency Confers Increased Protection against Visceral Leishmania Infection in Mice

  • Kevin W. Bruhn equal contributor mail,

    equal contributor Contributed equally to this work with: Kevin W. Bruhn, Chaitra Marathe

    kbruhn@labiomed.org

    Affiliation: Department of Medicine, Division of Dermatology and Infectious Diseases, Harbor-University of California Los Angeles Medical Center and Los Angeles Biomedical Research Institute, Torrance, California, United States of America

    X
  • Chaitra Marathe equal contributor,

    equal contributor Contributed equally to this work with: Kevin W. Bruhn, Chaitra Marathe

    Affiliation: Department of Pathology, Molecular Biology Institute, Howard Hughes Medical Institute, University of California Los Angeles, Los Angeles, California, United States of America

    Current address: NGM Biopharmaceuticals, South San Francisco, California, United States of America

    X
  • Ana Cláudia Maretti-Mira,

    Affiliation: Department of Medicine, Division of Dermatology and Infectious Diseases, Harbor-University of California Los Angeles Medical Center and Los Angeles Biomedical Research Institute, Torrance, California, United States of America

    X
  • Hong Nguyen,

    Affiliation: Department of Medicine, Division of Dermatology and Infectious Diseases, Harbor-University of California Los Angeles Medical Center and Los Angeles Biomedical Research Institute, Torrance, California, United States of America

    X
  • Jacquelyn Haskell,

    Affiliation: Department of Medicine, Division of Dermatology and Infectious Diseases, Harbor-University of California Los Angeles Medical Center and Los Angeles Biomedical Research Institute, Torrance, California, United States of America

    X
  • Thu Anh Tran,

    Affiliation: Department of Medicine, Division of Dermatology and Infectious Diseases, Harbor-University of California Los Angeles Medical Center and Los Angeles Biomedical Research Institute, Torrance, California, United States of America

    X
  • Veena Vanchinathan,

    Affiliation: Department of Medicine, Division of Dermatology and Infectious Diseases, Harbor-University of California Los Angeles Medical Center and Los Angeles Biomedical Research Institute, Torrance, California, United States of America

    X
  • Upasna Gaur,

    Affiliation: Departments of Internal Medicine, Epidemiology and Microbiology, University of Iowa and the Veterans Affairs Medical Center, Iowa City, Iowa, United States of America

    X
  • Mary E. Wilson,

    Affiliation: Departments of Internal Medicine, Epidemiology and Microbiology, University of Iowa and the Veterans Affairs Medical Center, Iowa City, Iowa, United States of America

    X
  • Peter Tontonoz,

    Affiliation: Department of Pathology, Molecular Biology Institute, Howard Hughes Medical Institute, University of California Los Angeles, Los Angeles, California, United States of America

    X
  • Noah Craft

    Affiliation: Department of Medicine, Division of Dermatology and Infectious Diseases, Harbor-University of California Los Angeles Medical Center and Los Angeles Biomedical Research Institute, Torrance, California, United States of America

    X
  • Published: November 16, 2010
  • DOI: 10.1371/journal.pntd.0000886

About the Authors

Kevin W. Bruhn, Ana Cláudia Maretti-Mira, Hong Nguyen, Jacquelyn Haskell, Thu Anh Tran, Veena Vanchinathan, Noah Craft
Department of Medicine, Division of Dermatology and Infectious Diseases, Harbor-University of California Los Angeles Medical Center and Los Angeles Biomedical Research Institute, Torrance, California, United States of America
Chaitra Marathe, Peter Tontonoz
Department of Pathology, Molecular Biology Institute, Howard Hughes Medical Institute, University of California Los Angeles, Los Angeles, California, United States of America
Upasna Gaur, Mary E. Wilson
Departments of Internal Medicine, Epidemiology and Microbiology, University of Iowa and the Veterans Affairs Medical Center, Iowa City, Iowa, United States of America

Corresponding Author

Email: kbruhn@labiomed.org

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: KWB CM ACMM HN UG NC. Performed the experiments: KWB CM ACMM HN JH TAT VV UG. Analyzed the data: KWB CM ACMM HN JH TAT UG MEW PT NC. Contributed reagents/materials/analysis tools: KWB CM MEW PT NC. Wrote the paper: KWB NC.