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Research Article

Granulomatous Reactivation during the Course of a Leprosy Infection: Reaction or Relapse

  • Maria Angela Bianconcini Trindade mail,

    angelatrindade@uol.com.br

    Affiliation: Health Institute, São Paulo State Health Department, São Paulo, São Paulo, Brazil

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  • Gil Benard,

    Affiliations: LIM 56 and 53, Division of Clinical Dermatology, Clinics Hospital, University of São Paulo, São Paulo, São Paulo, Brazil, Medical Mycology Laboratory, Tropical Medicine Institute, University of São Paulo, São Paulo, São Paulo, Brazil

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  • Somei Ura,

    Affiliation: Lauro de Souza Lima Institute, State Health Department, Bauru, São Paulo, Brazil

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  • Cássio Cesar Ghidella,

    Affiliation: Rondonópolis Health Service, State Health Department of Mato Grosso, Rondonópolis, Mato Grosso, Brazil

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  • João Carlos Regazzi Avelleira,

    Affiliation: Curupaiti Health Service, State Health Department of Rio de Janeiro, Curupaiti, Rio de Janeiro, Brazil

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  • Francisco Reis Vianna,

    Affiliation: Curupaiti Health Service, State Health Department of Rio de Janeiro, Curupaiti, Rio de Janeiro, Brazil

    X
  • Alfredo Bolchat Marques,

    Affiliation: Curupaiti Health Service, State Health Department of Rio de Janeiro, Curupaiti, Rio de Janeiro, Brazil

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  • Ben Naafs equal contributor,

    equal contributor Contributed equally to this work with: Ben Naafs, Raul Negrão Fleury

    Affiliation: Leiden University Medical Centre, Leiden, The Netherlands

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  • Raul Negrão Fleury equal contributor

    equal contributor Contributed equally to this work with: Ben Naafs, Raul Negrão Fleury

    Affiliation: Lauro de Souza Lima Institute, State Health Department, Bauru, São Paulo, Brazil

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  • Published: December 21, 2010
  • DOI: 10.1371/journal.pntd.0000921

About the Authors

Maria Angela Bianconcini Trindade
Health Institute, São Paulo State Health Department, São Paulo, São Paulo, Brazil
Gil Benard
LIM 56 and 53, Division of Clinical Dermatology, Clinics Hospital, University of São Paulo, São Paulo, São Paulo, Brazil
Gil Benard
Medical Mycology Laboratory, Tropical Medicine Institute, University of São Paulo, São Paulo, São Paulo, Brazil
Somei Ura, Raul Negrão Fleury
Lauro de Souza Lima Institute, State Health Department, Bauru, São Paulo, Brazil
Cássio Cesar Ghidella
Rondonópolis Health Service, State Health Department of Mato Grosso, Rondonópolis, Mato Grosso, Brazil
João Carlos Regazzi Avelleira, Francisco Reis Vianna, Alfredo Bolchat Marques
Curupaiti Health Service, State Health Department of Rio de Janeiro, Curupaiti, Rio de Janeiro, Brazil
Ben Naafs
Leiden University Medical Centre, Leiden, The Netherlands

Corresponding Author

Email: angelatrindade@uol.com.br

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MABT RNF. Performed the experiments: MABT RNF. Analyzed the data: MABT GB BN RNF. Contributed reagents/materials/analysis tools: MABT SU CCG JCRA FRV ABM RNF. Wrote the paper: MABT GB BN RNF.