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Research Article

Activities of Rifampin, Rifapentine and Clarithromycin Alone and in Combination against Mycobacterium ulcerans Disease in Mice

  • Deepak Almeida,

    Affiliation: Center for Tuberculosis Research, Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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  • Paul J. Converse,

    Affiliation: Center for Tuberculosis Research, Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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  • Zahoor Ahmad,

    Affiliation: Center for Tuberculosis Research, Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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  • Kelly E. Dooley,

    Affiliations: Center for Tuberculosis Research, Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Division of Clinical Pharmacology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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  • Eric L. Nuermberger,

    Affiliations: Center for Tuberculosis Research, Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America

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  • Jacques H. Grosset mail

    jgrosse4@jhmi.edu

    Affiliation: Center for Tuberculosis Research, Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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  • Published: January 04, 2011
  • DOI: 10.1371/journal.pntd.0000933

About the Authors

Deepak Almeida, Paul J. Converse, Zahoor Ahmad, Kelly E. Dooley, Eric L. Nuermberger, Jacques H. Grosset
Center for Tuberculosis Research, Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
Kelly E. Dooley
Division of Clinical Pharmacology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
Eric L. Nuermberger
Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America

Corresponding Author

Email: jgrosse4@jhmi.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DA PJC ELN JHG. Performed the experiments: DA PJC ZA. Analyzed the data: DA PJC KED ELN JHG. Contributed reagents/materials/analysis tools: DA KED ELN JHG. Wrote the paper: DA JHG.