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Research Article

DC-SIGN (CD209) Promoter −336 A/G Polymorphism Is Associated with Dengue Hemorrhagic Fever and Correlated to DC-SIGN Expression and Immune Augmentation

  • Lin Wang equal contributor,

    equal contributor Contributed equally to this work with: Lin Wang, Rong-Fu Chen

    Affiliations: Department of Pediatrics, Chang Gung Memorial Hospital-Kaohsiung Medical Center (CGMH-KMC), Kaohsiung, Taiwan, Graduate Institute of Clinical Medical Sciences, Chang Gung University College of Medicine, Kaohsiung, Taiwan

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  • Rong-Fu Chen equal contributor,

    equal contributor Contributed equally to this work with: Lin Wang, Rong-Fu Chen

    Affiliation: Department of Medical Research, CGMH-KMC, Kaohsiung, Taiwan

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  • Jien-Wei Liu,

    Affiliation: Division of Infectious Diseases, Department of Internal Medicine, CGMH-KMC, Kaohsiung, Taiwan

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  • Ing-Kit Lee,

    Affiliation: Division of Infectious Diseases, Department of Internal Medicine, CGMH-KMC, Kaohsiung, Taiwan

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  • Chiu-Ping Lee,

    Affiliation: Department of Medical Research, CGMH-KMC, Kaohsiung, Taiwan

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  • Ho-Chang Kuo,

    Affiliations: Department of Pediatrics, Chang Gung Memorial Hospital-Kaohsiung Medical Center (CGMH-KMC), Kaohsiung, Taiwan, Graduate Institute of Clinical Medical Sciences, Chang Gung University College of Medicine, Kaohsiung, Taiwan

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  • Shau-Ku Huang,

    Affiliation: Johns Hopkins Asthma and Allergy Center, Baltimore, Maryland, United States of America

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  • Kuender D. Yang mail

    yangkd@adm.cgmh.com.tw

    Affiliations: Department of Pediatrics, Chang Gung Memorial Hospital-Kaohsiung Medical Center (CGMH-KMC), Kaohsiung, Taiwan, Department of Medical Research, CGMH-KMC, Kaohsiung, Taiwan, Graduate Institute of Clinical Medical Sciences, Chang Gung University College of Medicine, Kaohsiung, Taiwan

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  • Published: January 04, 2011
  • DOI: 10.1371/journal.pntd.0000934

About the Authors

Lin Wang, Ho-Chang Kuo, Kuender D. Yang
Department of Pediatrics, Chang Gung Memorial Hospital-Kaohsiung Medical Center (CGMH-KMC), Kaohsiung, Taiwan
Rong-Fu Chen, Chiu-Ping Lee, Kuender D. Yang
Department of Medical Research, CGMH-KMC, Kaohsiung, Taiwan
Jien-Wei Liu, Ing-Kit Lee
Division of Infectious Diseases, Department of Internal Medicine, CGMH-KMC, Kaohsiung, Taiwan
Shau-Ku Huang
Johns Hopkins Asthma and Allergy Center, Baltimore, Maryland, United States of America
Lin Wang, Ho-Chang Kuo, Kuender D. Yang
Graduate Institute of Clinical Medical Sciences, Chang Gung University College of Medicine, Kaohsiung, Taiwan

Corresponding Author

Email: yangkd@adm.cgmh.com.tw

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: LW KDY. Performed the experiments: LW RFC CPL. Analyzed the data: LW RFC. Contributed reagents/materials/analysis tools: JWL IKL HCK SKH. Wrote the paper: LW RFC KDY.