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Research Article

Dengue in Thailand and Cambodia: An Assessment of the Degree of Underrecognized Disease Burden Based on Reported Cases

  • Ole Wichmann mail,

    WichmannO@rki.de

    Affiliation: Pediatric Dengue Vaccine Initiative, International Vaccine Institute (IVI), Seoul, Korea

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  • In-Kyu Yoon,

    Affiliation: Armed Forces Research Institute of Medical Sciences (AFRIMS), Bangkok, Thailand

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  • Sirenda Vong,

    Affiliation: Institut Pasteur in Cambodia, Phnom Penh, Cambodia

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  • Kriengsak Limkittikul,

    Affiliation: Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

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  • Robert V. Gibbons,

    Affiliation: Armed Forces Research Institute of Medical Sciences (AFRIMS), Bangkok, Thailand

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  • Mammen P. Mammen,

    Affiliation: Armed Forces Research Institute of Medical Sciences (AFRIMS), Bangkok, Thailand

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  • Sowath Ly,

    Affiliation: Institut Pasteur in Cambodia, Phnom Penh, Cambodia

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  • Philippe Buchy,

    Affiliation: Institut Pasteur in Cambodia, Phnom Penh, Cambodia

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  • Chukiat Sirivichayakul,

    Affiliation: Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

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  • Rome Buathong,

    Affiliation: Bureau of Epidemiology, Ministry of Public Health, Nonthaburi, Thailand

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  • Rekol Huy,

    Affiliation: National Dengue Control Program, Ministry of Health, Phnom Penh, Cambodia

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  • G. William Letson,

    Affiliation: Pediatric Dengue Vaccine Initiative, International Vaccine Institute (IVI), Seoul, Korea

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  • Arunee Sabchareon

    Affiliation: Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

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  • Published: March 29, 2011
  • DOI: 10.1371/journal.pntd.0000996

About the Authors

Ole Wichmann, G. William Letson
Pediatric Dengue Vaccine Initiative, International Vaccine Institute (IVI), Seoul, Korea
In-Kyu Yoon, Robert V. Gibbons, Mammen P. Mammen
Armed Forces Research Institute of Medical Sciences (AFRIMS), Bangkok, Thailand
Sirenda Vong, Sowath Ly, Philippe Buchy
Institut Pasteur in Cambodia, Phnom Penh, Cambodia
Kriengsak Limkittikul, Chukiat Sirivichayakul, Arunee Sabchareon
Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
Rome Buathong
Bureau of Epidemiology, Ministry of Public Health, Nonthaburi, Thailand
Rekol Huy
National Dengue Control Program, Ministry of Health, Phnom Penh, Cambodia

Corresponding Author

Email: WichmannO@rki.de

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: OW GWL. Performed the experiments: I-KY SV KL RVG MPM SL PB CS AS. Analyzed the data: OW. Contributed reagents/materials/analysis tools: I-KY SV KL RVG MPM SL PB CS RB RH AS. Wrote the paper: OW I-KY SV KL RVG MPM SL PB CS RB RH GWL AS.