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Research Article

Comparative Gene Expression Analysis throughout the Life Cycle of Leishmania braziliensis: Diversity of Expression Profiles among Clinical Isolates

  • Vanessa Adaui,

    Affiliations: Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru, Unit of Molecular Parasitology, Department of Parasitology, Institute of Tropical Medicine, Antwerp, Belgium

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  • Denis Castillo,

    Affiliations: Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru, Laboratorios de Investigación y Desarrollo, Facultad de Ciencias y Filosofía, Universidad Peruana Cayetano Heredia, Lima, Peru

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  • Mirko Zimic,

    Affiliation: Laboratorios de Investigación y Desarrollo, Facultad de Ciencias y Filosofía, Universidad Peruana Cayetano Heredia, Lima, Peru

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  • Andres Gutierrez,

    Affiliation: Laboratorios de Investigación y Desarrollo, Facultad de Ciencias y Filosofía, Universidad Peruana Cayetano Heredia, Lima, Peru

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  • Saskia Decuypere,

    Affiliation: Unit of Molecular Parasitology, Department of Parasitology, Institute of Tropical Medicine, Antwerp, Belgium

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  • Manu Vanaerschot,

    Affiliations: Unit of Molecular Parasitology, Department of Parasitology, Institute of Tropical Medicine, Antwerp, Belgium, Department of Biomedical Sciences, Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, Antwerp, Belgium

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  • Simonne De Doncker,

    Affiliation: Unit of Molecular Parasitology, Department of Parasitology, Institute of Tropical Medicine, Antwerp, Belgium

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  • Kathy Schnorbusch,

    Affiliations: Unit of Molecular Parasitology, Department of Parasitology, Institute of Tropical Medicine, Antwerp, Belgium, Department of Biomedical Sciences, Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, Antwerp, Belgium

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  • Ilse Maes,

    Affiliation: Unit of Molecular Parasitology, Department of Parasitology, Institute of Tropical Medicine, Antwerp, Belgium

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  • Gert Van der Auwera,

    Affiliation: Unit of Molecular Parasitology, Department of Parasitology, Institute of Tropical Medicine, Antwerp, Belgium

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  • Louis Maes,

    Affiliation: Department of Biomedical Sciences, Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, Antwerp, Belgium

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  • Alejandro Llanos-Cuentas,

    Affiliation: Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru

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  • Jorge Arevalo,

    Affiliations: Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru, Laboratorios de Investigación y Desarrollo, Facultad de Ciencias y Filosofía, Universidad Peruana Cayetano Heredia, Lima, Peru

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  • Jean-Claude Dujardin mail

    jcdujardin@itg.be

    Affiliations: Unit of Molecular Parasitology, Department of Parasitology, Institute of Tropical Medicine, Antwerp, Belgium, Department of Biomedical Sciences, Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, Antwerp, Belgium

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  • Published: May 10, 2011
  • DOI: 10.1371/journal.pntd.0001021

About the Authors

Vanessa Adaui, Denis Castillo, Alejandro Llanos-Cuentas, Jorge Arevalo
Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
Vanessa Adaui, Saskia Decuypere, Manu Vanaerschot, Simonne De Doncker, Kathy Schnorbusch, Ilse Maes, Gert Van der Auwera, Jean-Claude Dujardin
Unit of Molecular Parasitology, Department of Parasitology, Institute of Tropical Medicine, Antwerp, Belgium
Denis Castillo, Mirko Zimic, Andres Gutierrez, Jorge Arevalo
Laboratorios de Investigación y Desarrollo, Facultad de Ciencias y Filosofía, Universidad Peruana Cayetano Heredia, Lima, Peru
Manu Vanaerschot, Kathy Schnorbusch, Louis Maes, Jean-Claude Dujardin
Department of Biomedical Sciences, Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, Antwerp, Belgium

Corresponding Author

Email: jcdujardin@itg.be

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: VA JA J-CD. Performed the experiments: VA DC SDD KS. Analyzed the data: VA MZ AG MV IM GVdA J-CD. Contributed reagents/materials/analysis tools: MZ AL-C LM AG SD JA J-CD. Wrote the paper: VA MZ JA J-CD.