Advertisement
Research Article

Diagnostic Accuracy of Kato-Katz and FLOTAC for Assessing Anthelmintic Drug Efficacy

  • Stefanie Knopp,

    Affiliations: Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland, University of Basel, Basel, Switzerland

    X
  • Benjamin Speich,

    Affiliations: Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland, University of Basel, Basel, Switzerland

    X
  • Jan Hattendorf,

    Affiliations: Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland, University of Basel, Basel, Switzerland

    X
  • Laura Rinaldi,

    Affiliation: Department of Pathology and Animal Health, Regional Center for Monitoring Parasites (CREMOPAR), Regione Campania, University of Naples “Federico II”, Naples, Italy

    X
  • Khalfan A. Mohammed,

    Affiliation: Helminth Control Laboratory Unguja, Ministry of Health and Social Welfare, Zanzibar, United Republic of Tanzania

    X
  • I. Simba Khamis,

    Affiliation: Helminth Control Laboratory Unguja, Ministry of Health and Social Welfare, Zanzibar, United Republic of Tanzania

    X
  • Alisa S. Mohammed,

    Affiliation: Helminth Control Laboratory Unguja, Ministry of Health and Social Welfare, Zanzibar, United Republic of Tanzania

    X
  • Marco Albonico,

    Affiliations: Ivo de Carneri Foundation, Milano, Italy, Public Health Laboratory Ivo de Carneri, Chake-Chake, Pemba, United Republic of Tanzania

    X
  • David Rollinson,

    Affiliation: Wolfson Wellcome Biomedical Laboratories, Biomedical Parasitology Division, Department of Zoology, Natural History Museum, London, United Kingdom

    X
  • Hanspeter Marti,

    Affiliations: University of Basel, Basel, Switzerland, Department of Medical Services and Diagnostic, Swiss Tropical and Public Health Institute, Basel, Switzerland

    X
  • Giuseppe Cringoli,

    Affiliation: Department of Pathology and Animal Health, Regional Center for Monitoring Parasites (CREMOPAR), Regione Campania, University of Naples “Federico II”, Naples, Italy

    X
  • Jürg Utzinger mail

    juerg.utzinger@unibas.ch

    Affiliations: Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland, University of Basel, Basel, Switzerland

    X
  • Published: April 12, 2011
  • DOI: 10.1371/journal.pntd.0001036

About the Authors

Stefanie Knopp, Benjamin Speich, Jan Hattendorf, Jürg Utzinger
Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland
Stefanie Knopp, Benjamin Speich, Jan Hattendorf, Hanspeter Marti, Jürg Utzinger
University of Basel, Basel, Switzerland
Laura Rinaldi, Giuseppe Cringoli
Department of Pathology and Animal Health, Regional Center for Monitoring Parasites (CREMOPAR), Regione Campania, University of Naples “Federico II”, Naples, Italy
Khalfan A. Mohammed, I. Simba Khamis, Alisa S. Mohammed
Helminth Control Laboratory Unguja, Ministry of Health and Social Welfare, Zanzibar, United Republic of Tanzania
Marco Albonico
Ivo de Carneri Foundation, Milano, Italy
Marco Albonico
Public Health Laboratory Ivo de Carneri, Chake-Chake, Pemba, United Republic of Tanzania
David Rollinson
Wolfson Wellcome Biomedical Laboratories, Biomedical Parasitology Division, Department of Zoology, Natural History Museum, London, United Kingdom
Hanspeter Marti
Department of Medical Services and Diagnostic, Swiss Tropical and Public Health Institute, Basel, Switzerland

Corresponding Author

Email: juerg.utzinger@unibas.ch

Competing Interests

GC is the inventor and current patent holder of the FLOTAC apparatus. In case the current broad-scale validation of the FLOTAC technique will be successful, the method will be licensed free of charge to the WHO and interested public non-commercial research centers. None of the other authors has any conflict of interest concerning the work reported in this paper.

Author Contributions

Conceived and designed the experiments: SK BS LR KAM MA DR HM GC JU. Performed the experiments: SK BS LR ISK ASM. Analyzed the data: SK JH. Contributed reagents/materials/analysis tools: JH KAM ISK DR HM GC JU. Wrote the paper: SK BS JH LR KAM ISK ASM MA DR HM GC JU.