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Research Article

Testing the Efficacy of a Multi-Component DNA-Prime/DNA-Boost Vaccine against Trypanosoma cruzi Infection in Dogs

  • José E. Aparicio-Burgos,

    Affiliation: Centro de Investigación y Estudios Avanzados, Universidad Autónoma de Estado de México, Toluca, México

    X
  • Laucel Ochoa-García,

    Affiliation: Centro de Investigación y Estudios Avanzados, Universidad Autónoma de Estado de México, Toluca, México

    X
  • José Antonio Zepeda-Escobar,

    Affiliation: Centro de Investigación y Estudios Avanzados, Universidad Autónoma de Estado de México, Toluca, México

    X
  • Shivali Gupta,

    Affiliation: Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, United States of America

    X
  • Monisha Dhiman,

    Affiliation: Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, United States of America

    X
  • José Simón Martínez,

    Affiliation: Centro de Investigación y Estudios Avanzados, Universidad Autónoma de Estado de México, Toluca, México

    X
  • Roberto Montes de Oca-Jiménez,

    Affiliation: Centro de Investigación y Estudios Avanzados, Universidad Autónoma de Estado de México, Toluca, México

    X
  • Margarita Val Arreola,

    Affiliation: Cardiology Clinic, Irapuato, México

    X
  • Alberto Barbabosa-Pliego,

    Affiliation: Centro de Investigación y Estudios Avanzados, Universidad Autónoma de Estado de México, Toluca, México

    X
  • Juan C. Vázquez-Chagoyán mail,

    nigarg@utmb.edu (NJG); jcvch@yahoo.com (JCV-C)

    Affiliation: Centro de Investigación y Estudios Avanzados, Universidad Autónoma de Estado de México, Toluca, México

    X
  • Nisha Jain Garg mail

    nigarg@utmb.edu (NJG); jcvch@yahoo.com (JCV-C)

    Affiliations: Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, United States of America, Department of Pathology, University of Texas Medical Branch, Galveston, Texas, United States of America, Faculty of the Institute for Human Infections and Immunity, and the Sealy Center for Vaccine Development, University of Texas Medical Branch, Galveston, Texas, United States of America

    X
  • Published: May 17, 2011
  • DOI: 10.1371/journal.pntd.0001050

About the Authors

José E. Aparicio-Burgos, Laucel Ochoa-García, José Antonio Zepeda-Escobar, José Simón Martínez, Roberto Montes de Oca-Jiménez, Alberto Barbabosa-Pliego, Juan C. Vázquez-Chagoyán
Centro de Investigación y Estudios Avanzados, Universidad Autónoma de Estado de México, Toluca, México
Shivali Gupta, Monisha Dhiman, Nisha Jain Garg
Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, United States of America
Margarita Val Arreola
Cardiology Clinic, Irapuato, México
Nisha Jain Garg
Department of Pathology, University of Texas Medical Branch, Galveston, Texas, United States of America
Nisha Jain Garg
Faculty of the Institute for Human Infections and Immunity, and the Sealy Center for Vaccine Development, University of Texas Medical Branch, Galveston, Texas, United States of America

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JCV-C NJG. Performed the experiments: JEAB LO-G JAZ-E SG MD JSM RMdO-J MVA AB-P. Analyzed the data: JEAB JAZ-E SG MD RMdO-J MVA AB-P JCV-C. Contributed reagents/materials/analysis tools: JCV-C NJG. Wrote the paper: SG JCV-C NJG.