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Research Article

A New Approach to Dengue Fatal Cases Diagnosis: NS1 Antigen Capture in Tissues

  • Monique da Rocha Queiroz Lima,

    Affiliation: Flavivirus Laboratory, Oswaldo Cruz Institute, Rio de Janeiro, Brazil

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  • Rita Maria Ribeiro Nogueira,

    Affiliation: Flavivirus Laboratory, Oswaldo Cruz Institute, Rio de Janeiro, Brazil

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  • Hermann Gonçalves Schatzmayr,

    Affiliation: Flavivirus Laboratory, Oswaldo Cruz Institute, Rio de Janeiro, Brazil

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  • Ana Maria Bispo de Filippis,

    Affiliation: Flavivirus Laboratory, Oswaldo Cruz Institute, Rio de Janeiro, Brazil

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  • Daniel Limonta,

    Affiliation: National Reference Laboratory for Dengue, Virology Department, PAHO/WHO Collaborating Center for the Study of Dengue and Its Vector, Pedro Kourí Institute of Tropical Medicine, Havana, Cuba

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  • Flavia Barreto dos Santos mail

    flaviab@ioc.fiocruz.br

    Affiliation: Flavivirus Laboratory, Oswaldo Cruz Institute, Rio de Janeiro, Brazil

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  • Published: May 03, 2011
  • DOI: 10.1371/journal.pntd.0001147

About the Authors

Monique da Rocha Queiroz Lima, Rita Maria Ribeiro Nogueira, Hermann Gonçalves Schatzmayr, Ana Maria Bispo de Filippis, Flavia Barreto dos Santos
Flavivirus Laboratory, Oswaldo Cruz Institute, Rio de Janeiro, Brazil
Daniel Limonta
National Reference Laboratory for Dengue, Virology Department, PAHO/WHO Collaborating Center for the Study of Dengue and Its Vector, Pedro Kourí Institute of Tropical Medicine, Havana, Cuba

Corresponding Author

Email: flaviab@ioc.fiocruz.br

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: FBdS RMRN HGS. Performed the experiments: MdRQL. Analyzed the data: MdRQL DL AMBdF. Contributed reagents/materials/analysis tools: RMRN. Wrote the paper: MdRQL FBdS DL.