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Research Article

The Early Clinical Features of Dengue in Adults: Challenges for Early Clinical Diagnosis

  • Jenny G. H. Low,

    Affiliation: Communicable Diseases Centre, Tan Tock Seng Hospital, Singapore, Singapore

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  • Adrian Ong,

    Affiliation: Communicable Diseases Centre, Tan Tock Seng Hospital, Singapore, Singapore

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  • Li Kiang Tan,

    Affiliation: Environmental Health Institute, National Environment Agency, Singapore, Singapore

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  • Shera Chaterji,

    Affiliation: Duke-NUS Graduate Medical School, Singapore, Singapore

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  • Angelia Chow,

    Affiliation: Duke-NUS Graduate Medical School, Singapore, Singapore

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  • Wen Yan Lim,

    Affiliation: Duke-NUS Graduate Medical School, Singapore, Singapore

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  • Koon Wui Lee,

    Affiliation: DSO National Laboratories, Singapore, Singapore

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  • Robert Chua,

    Affiliation: Duke-NUS Graduate Medical School, Singapore, Singapore

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  • Choon Rong Chua,

    Affiliation: Environmental Health Institute, National Environment Agency, Singapore, Singapore

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  • Sharon W. S. Tan,

    Affiliation: Environmental Health Institute, National Environment Agency, Singapore, Singapore

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  • Yin Bun Cheung,

    Affiliations: Duke-NUS Graduate Medical School, Singapore, Singapore, Singapore Clinical Research Institute, Singapore, Singapore

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  • Martin L. Hibberd,

    Affiliation: Genome Institute of Singapore, Singapore, Singapore

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  • Subhash G. Vasudevan,

    Affiliation: Duke-NUS Graduate Medical School, Singapore, Singapore

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  • Lee-Ching Ng,

    Affiliation: Environmental Health Institute, National Environment Agency, Singapore, Singapore

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  • Yee Sin Leo,

    Affiliation: Communicable Diseases Centre, Tan Tock Seng Hospital, Singapore, Singapore

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  • Eng Eong Ooi mail

    engeong.ooi@duke-nus.edu.sg

    Affiliations: Duke-NUS Graduate Medical School, Singapore, Singapore, DSO National Laboratories, Singapore, Singapore

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  • Published: May 31, 2011
  • DOI: 10.1371/journal.pntd.0001191

About the Authors

Jenny G. H. Low, Adrian Ong, Yee Sin Leo
Communicable Diseases Centre, Tan Tock Seng Hospital, Singapore, Singapore
Li Kiang Tan, Choon Rong Chua, Sharon W. S. Tan, Lee-Ching Ng
Environmental Health Institute, National Environment Agency, Singapore, Singapore
Shera Chaterji, Angelia Chow, Wen Yan Lim, Robert Chua, Yin Bun Cheung, Subhash G. Vasudevan, Eng Eong Ooi
Duke-NUS Graduate Medical School, Singapore, Singapore
Koon Wui Lee, Eng Eong Ooi
DSO National Laboratories, Singapore, Singapore
Yin Bun Cheung
Singapore Clinical Research Institute, Singapore, Singapore
Martin L. Hibberd
Genome Institute of Singapore, Singapore, Singapore

Corresponding Author

Email: engeong.ooi@duke-nus.edu.sg

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JGHL AO MLH SGV EEO. Performed the experiments: JGHL AO LKT SC AC WYL KWL RC CRC SWST. Analyzed the data: SC YBC EEO. Contributed reagents/materials/analysis tools: L-CN YSL. Wrote the paper: JGHL AO EEO.