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Research Article

Synergism between Prior Anisakis simplex Infections and Intake of NSAIDs, on the Risk of Upper Digestive Bleeding: A Case-Control Study

  • Florencio M. Ubeira,

    Affiliation: Department of Microbiology and Parasitology, Faculty of Pharmacy, University of Santiago de Compostela, Santiago de Compostela, Spain

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  • Ana M. Anadón,

    Affiliation: Department of Microbiology and Parasitology, Faculty of Pharmacy, University of Santiago de Compostela, Santiago de Compostela, Spain

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  • Angel Salgado,

    Affiliations: Consortium for Biomedical Research in Epidemiology and Public Health (CIBER en Epidemiología y Salud Pública - CIBERESP), Santiago de Compostela, Spain, Department of Preventive Medicine and Public Health, University of Santiago de Compostela, Santiago de Compostela, Spain

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  • Alfonso Carvajal,

    Affiliation: Department of Pharmacology, Faculty of Medicine, University of Valladolid, Valladolid, Spain

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  • Sara Ortega,

    Affiliation: Department of Pharmacology, Faculty of Medicine, University of Valladolid, Valladolid, Spain

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  • Carmelo Aguirre,

    Affiliation: Pharmacosurveillance Unit, Galdakao-Usansolo Hospital, Galdakao, Spain

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  • María José López-Goikoetxea,

    Affiliation: Microbiology Service, Galdakao-Usansolo Hospital, Galdakao, Spain

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  • Luisa Ibanez,

    Affiliation: Department of Pharmacology, Therapeutics and Toxicology, Autonomous University, Catalonian Institute of Pharmacology, Clinical Pharmacology Service, Vall d'Hebron University Teaching Hospital, Barcelona, Spain

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  • Adolfo Figueiras mail

    adolfo.figueiras@usc.es

    Affiliations: Consortium for Biomedical Research in Epidemiology and Public Health (CIBER en Epidemiología y Salud Pública - CIBERESP), Santiago de Compostela, Spain, Department of Preventive Medicine and Public Health, University of Santiago de Compostela, Santiago de Compostela, Spain

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  • Published: June 28, 2011
  • DOI: 10.1371/journal.pntd.0001214

About the Authors

Florencio M. Ubeira, Ana M. Anadón
Department of Microbiology and Parasitology, Faculty of Pharmacy, University of Santiago de Compostela, Santiago de Compostela, Spain
Angel Salgado, Adolfo Figueiras
Consortium for Biomedical Research in Epidemiology and Public Health (CIBER en Epidemiología y Salud Pública - CIBERESP), Santiago de Compostela, Spain
Angel Salgado, Adolfo Figueiras
Department of Preventive Medicine and Public Health, University of Santiago de Compostela, Santiago de Compostela, Spain
Alfonso Carvajal, Sara Ortega
Department of Pharmacology, Faculty of Medicine, University of Valladolid, Valladolid, Spain
Carmelo Aguirre
Pharmacosurveillance Unit, Galdakao-Usansolo Hospital, Galdakao, Spain
María José López-Goikoetxea
Microbiology Service, Galdakao-Usansolo Hospital, Galdakao, Spain
Luisa Ibanez
Department of Pharmacology, Therapeutics and Toxicology, Autonomous University, Catalonian Institute of Pharmacology, Clinical Pharmacology Service, Vall d'Hebron University Teaching Hospital, Barcelona, Spain

Corresponding Author

Email: adolfo.figueiras@usc.es

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: FMU AF. Performed the experiments: FMU AMA AS AF. Analyzed the data: FMU AS AF AC SO CA MJL-G LI. Contributed reagents/materials/analysis tools: AF FMU AC SO CA MJL-G LI. Wrote the paper: FMU AF. Other: AC SO CA MJL-G LI AF.