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Research Article

Clinical and Virological Factors Influencing the Performance of a NS1 Antigen-Capture Assay and Potential Use as a Marker of Dengue Disease Severity

  • Veasna Duong,

    Affiliation: Institut Pasteur in Cambodia, Réseau International des Instituts Pasteur, Phnom Penh, Cambodia

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  • Sowath Ly,

    Affiliation: Institut Pasteur in Cambodia, Réseau International des Instituts Pasteur, Phnom Penh, Cambodia

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  • Patrich Lorn Try,

    Affiliation: Paediatric Department, Kampong Cham Provincial Hospital, Kampong Cham, Cambodia

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  • Anne Tuiskunen,

    Affiliation: Swedish Center for Infectious Disease Control, Stockholm, Sweden

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  • Sivuth Ong,

    Affiliation: Institut Pasteur in Cambodia, Réseau International des Instituts Pasteur, Phnom Penh, Cambodia

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  • Norith Chroeung,

    Affiliation: Paediatric Department, Kampong Cham Provincial Hospital, Kampong Cham, Cambodia

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  • Ake Lundkvist,

    Affiliation: Swedish Center for Infectious Disease Control, Stockholm, Sweden

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  • Isabelle Leparc-Goffart,

    Affiliation: Unité de Virologie, Institut de Médecine Tropicale du Service de Santé des Armées, Marseille, France

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  • Vincent Deubel,

    Affiliation: Institut Pasteur in Cambodia, Réseau International des Instituts Pasteur, Phnom Penh, Cambodia

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  • Sirenda Vong,

    Affiliation: Institut Pasteur in Cambodia, Réseau International des Instituts Pasteur, Phnom Penh, Cambodia

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  • Philippe Buchy mail

    pbuchy@pasteur-kh.org

    Affiliation: Institut Pasteur in Cambodia, Réseau International des Instituts Pasteur, Phnom Penh, Cambodia

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  • Published: July 19, 2011
  • DOI: 10.1371/journal.pntd.0001244

About the Authors

Veasna Duong, Sowath Ly, Sivuth Ong, Vincent Deubel, Sirenda Vong, Philippe Buchy
Institut Pasteur in Cambodia, Réseau International des Instituts Pasteur, Phnom Penh, Cambodia
Patrich Lorn Try, Norith Chroeung
Paediatric Department, Kampong Cham Provincial Hospital, Kampong Cham, Cambodia
Anne Tuiskunen, Ake Lundkvist
Swedish Center for Infectious Disease Control, Stockholm, Sweden
Isabelle Leparc-Goffart
Unité de Virologie, Institut de Médecine Tropicale du Service de Santé des Armées, Marseille, France

Corresponding Author

Email: pbuchy@pasteur-kh.org

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: PB V. Duong V. Deubel. Performed the experiments: V. Duong SO. Analyzed the data: V. Duong SL SV PB. Contributed reagents/materials/analysis tools: PLT AT NC AL ILG. Wrote the paper: V. Duong AL ILG V. Deubel SV PB.