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Research Article

Efficacy and Safety of Artemether in the Treatment of Chronic Fascioliasis in Egypt: Exploratory Phase-2 Trials

  • Jennifer Keiser mail,

    jennifer.keiser@unibas.ch

    Affiliations: Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland, University of Basel, Basel, Switzerland

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  • Hanan Sayed,

    Affiliation: Public Health Department, Theodor Bilharz Research Institute, Giza, Egypt

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  • Maged El-Ghanam,

    Affiliation: Hepatogastroenterology Department, Theodor Bilharz Research Institute, Giza, Egypt

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  • Hoda Sabry,

    Affiliation: Parasitology Department, Theodor Bilharz Research Institute, Giza, Egypt

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  • Saad Anani,

    Affiliation: Ministry of Health and Population, Alexandria Governorate, Alexandria, Egypt

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  • Aly El-Wakeel,

    Affiliation: Ministry of Health and Population, Behera Governorate, Behera, Egypt

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  • Christoph Hatz,

    Affiliations: University of Basel, Basel, Switzerland, Department of Medical Services and Diagnostic, Swiss Tropical and Public Health Institute, Basel, Switzerland, Institute for Social and Preventive Medicine, University of Zurich, Zurich, Switzerland

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  • Jürg Utzinger,

    Affiliations: University of Basel, Basel, Switzerland, Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland

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  • Sayed Seif el-Din,

    Affiliation: Pharmacology Department, Theodor Bilharz Research Institute, Giza, Egypt

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  • Walaa El-Maadawy,

    Affiliation: Pharmacology Department, Theodor Bilharz Research Institute, Giza, Egypt

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  • Sanaa Botros

    Affiliation: Pharmacology Department, Theodor Bilharz Research Institute, Giza, Egypt

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  • Published: September 06, 2011
  • DOI: 10.1371/journal.pntd.0001285

About the Authors

Jennifer Keiser
Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland
Jennifer Keiser, Christoph Hatz, Jürg Utzinger
University of Basel, Basel, Switzerland
Hanan Sayed
Public Health Department, Theodor Bilharz Research Institute, Giza, Egypt
Maged El-Ghanam
Hepatogastroenterology Department, Theodor Bilharz Research Institute, Giza, Egypt
Hoda Sabry
Parasitology Department, Theodor Bilharz Research Institute, Giza, Egypt
Saad Anani
Ministry of Health and Population, Alexandria Governorate, Alexandria, Egypt
Aly El-Wakeel
Ministry of Health and Population, Behera Governorate, Behera, Egypt
Christoph Hatz
Department of Medical Services and Diagnostic, Swiss Tropical and Public Health Institute, Basel, Switzerland
Christoph Hatz
Institute for Social and Preventive Medicine, University of Zurich, Zurich, Switzerland
Jürg Utzinger
Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland
Sayed Seif el-Din, Walaa El-Maadawy, Sanaa Botros
Pharmacology Department, Theodor Bilharz Research Institute, Giza, Egypt

Corresponding Author

Email: jennifer.keiser@unibas.ch

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JK JU CH SB. Performed the experiments: H. Sayed ME-G H. Sabry SA AE-W SSe-D WE-M SB. Analyzed the data: JK H. Sayed SB. Wrote the paper: JK CH JU SB.