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Research Article

Melarsoprol Cyclodextrin Inclusion Complexes as Promising Oral Candidates for the Treatment of Human African Trypanosomiasis

  • Jean Rodgers equal contributor,

    equal contributor Contributed equally to this work with: Jean Rodgers, Amy Jones

    Affiliation: Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom

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  • Amy Jones equal contributor,

    equal contributor Contributed equally to this work with: Jean Rodgers, Amy Jones

    Affiliation: Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom

    X
  • Stéphane Gibaud,

    Affiliation: Laboratoire de Pharmacie Clinique, Nancy Université, Nancy, France

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  • Barbara Bradley,

    Affiliation: Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom

    X
  • Christopher McCabe,

    Affiliation: Institute of Neuroscience and Psychology, Glasgow Experimental MRI Centre, University of Glasgow, Glasgow, United Kingdom

    X
  • Michael P. Barrett,

    Affiliation: Wellcome Trust Centre of Molecular Parasitology, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom

    X
  • George Gettinby,

    Affiliation: Department of Mathematics and Statistics, University of Strathclyde, Glasgow, United Kingdom

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  • Peter G. E. Kennedy mail

    Peter.Kennedy@glasgow.ac.uk

    Affiliation: Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom

    X
  • Published: September 06, 2011
  • DOI: 10.1371/journal.pntd.0001308

About the Authors

Jean Rodgers, Amy Jones, Barbara Bradley, Peter G. E. Kennedy
Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom
Stéphane Gibaud
Laboratoire de Pharmacie Clinique, Nancy Université, Nancy, France
Christopher McCabe
Institute of Neuroscience and Psychology, Glasgow Experimental MRI Centre, University of Glasgow, Glasgow, United Kingdom
Michael P. Barrett
Wellcome Trust Centre of Molecular Parasitology, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom
George Gettinby
Department of Mathematics and Statistics, University of Strathclyde, Glasgow, United Kingdom

Corresponding Author

Email: Peter.Kennedy@glasgow.ac.uk

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JR AJ PGEK MPB. Performed the experiments: AJ BB CM. Analyzed the data: AJ JR PGEK GG. Contributed reagents/materials/analysis tools: SG. Wrote the paper: JR PGEK.