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Research Article

Histopathological Changes and Clinical Responses of Buruli Ulcer Plaque Lesions during Chemotherapy: A Role for Surgical Removal of Necrotic Tissue?

  • Marie-Thérèse Ruf equal contributor,

    equal contributor Contributed equally to this work with: Marie-Thérèse Ruf, Ghislain Emmanuel Sopoh

    Affiliations: Swiss Tropical and Public Health Institute, Basel, Switzerland, University of Basel, Basel, Switzerland

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  • Ghislain Emmanuel Sopoh equal contributor,

    equal contributor Contributed equally to this work with: Marie-Thérèse Ruf, Ghislain Emmanuel Sopoh

    Affiliation: Centre de Depistage et de Traitement de l'Ulcere de Buruli d'Allada, Allada, Benin

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  • Luc Valère Brun,

    Affiliation: Laboratoire d'Anatomie et Cytologie Pathologiques, Université de Parakou, Parakou, Benin

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  • Ange Dodji Dossou,

    Affiliation: Centre de Depistage et de Traitement de l'Ulcere de Buruli d'Allada, Allada, Benin

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  • Yves Thierry Barogui,

    Affiliation: Centre de Depistage et de Traitement de l'Ulcere de Buruli de Lalo, Lalo, Benin

    X
  • Roch Christian Johnson,

    Affiliation: Fondation Raoul Follereau, Cotonou, Bénin

    X
  • Gerd Pluschke mail

    gerd.pluschke@unibas.ch

    Affiliations: Swiss Tropical and Public Health Institute, Basel, Switzerland, University of Basel, Basel, Switzerland

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  • Published: September 27, 2011
  • DOI: 10.1371/journal.pntd.0001334

About the Authors

Marie-Thérèse Ruf, Gerd Pluschke
Swiss Tropical and Public Health Institute, Basel, Switzerland
Marie-Thérèse Ruf, Gerd Pluschke
University of Basel, Basel, Switzerland
Ghislain Emmanuel Sopoh, Ange Dodji Dossou
Centre de Depistage et de Traitement de l'Ulcere de Buruli d'Allada, Allada, Benin
Luc Valère Brun
Laboratoire d'Anatomie et Cytologie Pathologiques, Université de Parakou, Parakou, Benin
Yves Thierry Barogui
Centre de Depistage et de Traitement de l'Ulcere de Buruli de Lalo, Lalo, Benin
Roch Christian Johnson
Fondation Raoul Follereau, Cotonou, Bénin

Corresponding Author

Email: gerd.pluschke@unibas.ch

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: M-TR GES RCJ GP. Performed the experiments: M-TR GES. Analyzed the data: M-TR GES RCJ GP. Contributed reagents/materials/analysis tools: GES LVB ADD YTB. Wrote the paper: M-TR GES GP.