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Research Article

Human Cellular Immune Response to the Saliva of Phlebotomus papatasi Is Mediated by IL-10-Producing CD8+ T Cells and Th1-Polarized CD4+ Lymphocytes

  • Maha Abdeladhim equal contributor,

    equal contributor Contributed equally to this work with: Maha Abdeladhim, Mélika Ben Ahmed

    Affiliation: Department of Clinical Immunology, Pasteur Institute of Tunis, Tunis, Tunisia

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  • Mélika Ben Ahmed equal contributor mail,

    equal contributor Contributed equally to this work with: Maha Abdeladhim, Mélika Ben Ahmed

    melika.benahmed@pasteur.rns.tn

    Affiliation: Department of Clinical Immunology, Pasteur Institute of Tunis, Tunis, Tunisia

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  • Soumaya Marzouki,

    Affiliation: Department of Clinical Immunology, Pasteur Institute of Tunis, Tunis, Tunisia

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  • Nadia Belhadj Hmida,

    Affiliation: Department of Clinical Immunology, Pasteur Institute of Tunis, Tunis, Tunisia

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  • Thouraya Boussoffara,

    Affiliation: LIVGM, Pasteur Institute of Tunis, Tunis, Tunisia

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  • Nabil Belhaj Hamida,

    Affiliation: Department of Medical Epidemiology, Pasteur Institute of Tunis, Tunis, Tunisia

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  • Afif Ben Salah,

    Affiliation: Department of Medical Epidemiology, Pasteur Institute of Tunis, Tunis, Tunisia

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  • Hechmi Louzir

    Affiliations: Department of Clinical Immunology, Pasteur Institute of Tunis, Tunis, Tunisia, LIVGM, Pasteur Institute of Tunis, Tunis, Tunisia

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  • Published: October 04, 2011
  • DOI: 10.1371/journal.pntd.0001345

About the Authors

Maha Abdeladhim, Mélika Ben Ahmed, Soumaya Marzouki, Nadia Belhadj Hmida, Hechmi Louzir
Department of Clinical Immunology, Pasteur Institute of Tunis, Tunis, Tunisia
Thouraya Boussoffara, Hechmi Louzir
LIVGM, Pasteur Institute of Tunis, Tunis, Tunisia
Nabil Belhaj Hamida, Afif Ben Salah
Department of Medical Epidemiology, Pasteur Institute of Tunis, Tunis, Tunisia

Corresponding Author

Email: melika.benahmed@pasteur.rns.tn

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MBA MA HL. Performed the experiments: MBA MA SM Nadia Belhadj Hmida. Analyzed the data: MBA MA HL. Contributed reagents/materials/analysis tools: TB Nabil Belhaj Hmida ABS. Wrote the paper: MBA MA HL.