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Research Article

Cell-Associated Flagella Enhance the Protection Conferred by Mucosally-Administered Attenuated Salmonella Paratyphi A Vaccines

  • Orit Gat,

    Affiliations: Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, Maryland, United States of America, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

    X
  • James E. Galen mail,

    jgalen@medicine.umaryland.edu

    Affiliations: Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, Maryland, United States of America, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

    X
  • Sharon Tennant,

    Affiliations: Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, Maryland, United States of America, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

    X
  • Raphael Simon,

    Affiliations: Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, Maryland, United States of America, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

    X
  • William C. Blackwelder,

    Affiliations: Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, Maryland, United States of America, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

    X
  • David J. Silverman,

    Affiliation: Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

    X
  • Marcela F. Pasetti,

    Affiliations: Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, Maryland, United States of America, Department of Pediatrics, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

    X
  • Myron M. Levine

    Affiliations: Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, Maryland, United States of America, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America, Department of Pediatrics, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

    X
  • Published: November 01, 2011
  • DOI: 10.1371/journal.pntd.0001373

About the Authors

Orit Gat, James E. Galen, Sharon Tennant, Raphael Simon, William C. Blackwelder, Marcela F. Pasetti, Myron M. Levine
Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, Maryland, United States of America
Orit Gat, James E. Galen, Sharon Tennant, Raphael Simon, William C. Blackwelder, Myron M. Levine
Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America
David J. Silverman
Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America
Marcela F. Pasetti, Myron M. Levine
Department of Pediatrics, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

Corresponding Author

Email: jgalen@medicine.umaryland.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: OG JEG ST MML. Performed the experiments: OG DJS. Analyzed the data: OG JEG WCB MFP. Contributed reagents/materials/analysis tools: RS. Wrote the paper: OG JEG ST RS WCB DJS MFP MML.