Advertisement
Research Article

Elevated Adaptive Immune Responses Are Associated with Latent Infections of Wuchereria bancrofti

  • Kathrin Arndts equal contributor,

    equal contributor Contributed equally to this work with: Kathrin Arndts, Susanne Deininger

    Affiliation: Institute of Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Bonn, Germany

    X
  • Susanne Deininger equal contributor,

    equal contributor Contributed equally to this work with: Kathrin Arndts, Susanne Deininger

    Affiliation: Institute of Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Bonn, Germany

    X
  • Sabine Specht,

    Affiliation: Institute of Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Bonn, Germany

    X
  • Ute Klarmann,

    Affiliations: Institute of Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Bonn, Germany, Institute of Medical Biometry, Informatics and Epidemiology, University Hospital Bonn, Bonn, Germany

    X
  • Sabine Mand,

    Affiliation: Institute of Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Bonn, Germany

    X
  • Tomabu Adjobimey,

    Affiliation: Institute of Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Bonn, Germany

    X
  • Alexander Y. Debrah,

    Affiliations: Kumasi Centre for Collaborative Research in Tropical Medicine, Kumasi, Ghana, Faculty of Allied Health Sciences, Department of Theoretical and Applied Biology, and School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana

    X
  • Linda Batsa,

    Affiliation: Kumasi Centre for Collaborative Research in Tropical Medicine, Kumasi, Ghana

    X
  • Alexander Kwarteng,

    Affiliation: Kumasi Centre for Collaborative Research in Tropical Medicine, Kumasi, Ghana

    X
  • Christian Epp,

    Affiliation: Department für Infektiologie, Parasitologie, Universitätsklinikum Heidelberg, Heidelberg, Germany

    X
  • Mark Taylor,

    Affiliation: Liverpool School of Tropical Medicine, Liverpool, United Kingdom

    X
  • Ohene Adjei,

    Affiliations: Kumasi Centre for Collaborative Research in Tropical Medicine, Kumasi, Ghana, Faculty of Allied Health Sciences, Department of Theoretical and Applied Biology, and School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana

    X
  • Laura E. Layland mail,

    laura.layland@microbiology-bonn.de

    Affiliation: Institute of Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Bonn, Germany

    These authors also contributed equally to this work.

    X
  • Achim Hoerauf

    Affiliation: Institute of Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Bonn, Germany

    These authors also contributed equally to this work.

    X
  • Published: April 03, 2012
  • DOI: 10.1371/journal.pntd.0001611

About the Authors

Kathrin Arndts, Susanne Deininger, Sabine Specht, Ute Klarmann, Sabine Mand, Tomabu Adjobimey, Laura E. Layland, Achim Hoerauf
Institute of Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Bonn, Germany
Ute Klarmann
Institute of Medical Biometry, Informatics and Epidemiology, University Hospital Bonn, Bonn, Germany
Alexander Y. Debrah, Linda Batsa, Alexander Kwarteng, Ohene Adjei
Kumasi Centre for Collaborative Research in Tropical Medicine, Kumasi, Ghana
Alexander Y. Debrah, Ohene Adjei
Faculty of Allied Health Sciences, Department of Theoretical and Applied Biology, and School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana
Christian Epp
Department für Infektiologie, Parasitologie, Universitätsklinikum Heidelberg, Heidelberg, Germany
Mark Taylor
Liverpool School of Tropical Medicine, Liverpool, United Kingdom

Corresponding Author

Email: laura.layland@microbiology-bonn.de

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SS LEL MT OA AH. Performed the experiments: KA SD SM TA AYD LB AK. Analyzed the data: KA SD UK LEL AH. Contributed reagents/materials/analysis tools: CE UK. Wrote the paper: KA SD LEL AH.