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Research Article

The Sigma Class Glutathione Transferase from the Liver Fluke Fasciola hepatica

  • E. James LaCourse,

    Affiliations: Institute of Biological, Environmental and Rural Sciences, Aberystwyth University, Aberystwyth, Wales, United Kingdom, Molecular and Biochemical Parasitology Group, Liverpool School of Tropical Medicine, Liverpool, England, United Kingdom

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  • Samirah Perally,

    Affiliation: Institute of Biological, Environmental and Rural Sciences, Aberystwyth University, Aberystwyth, Wales, United Kingdom

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  • Russell M. Morphew mail,

    rom@aber.ac.uk

    Affiliation: Institute of Biological, Environmental and Rural Sciences, Aberystwyth University, Aberystwyth, Wales, United Kingdom

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  • Joseph V. Moxon,

    Affiliation: Institute of Biological, Environmental and Rural Sciences, Aberystwyth University, Aberystwyth, Wales, United Kingdom

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  • Mark Prescott,

    Affiliation: School of Biological Sciences, University of Liverpool, Liverpool, England, United Kingdom

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  • David J. Dowling,

    Affiliation: Faculty of Science and Health, Dublin City University, Dublin, Ireland

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  • Sandra M. O'Neill,

    Affiliation: Faculty of Science and Health, Dublin City University, Dublin, Ireland

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  • Anja Kipar,

    Affiliation: Faculty of Veterinary Science, University of Liverpool, Liverpool, England, United Kingdom

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  • Udo Hetzel,

    Affiliation: Faculty of Veterinary Science, University of Liverpool, Liverpool, England, United Kingdom

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  • Elizabeth Hoey,

    Affiliation: School of Biological Sciences, Queen's University of Belfast, Belfast, Northern Ireland, United Kingdom

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  • Rafael Zafra,

    Affiliation: School of Veterinary Medicine, University of Córdoba, Córdoba, Spain

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  • Leandro Buffoni,

    Affiliation: School of Veterinary Medicine, University of Córdoba, Córdoba, Spain

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  • José Pérez Arévalo,

    Affiliation: School of Veterinary Medicine, University of Córdoba, Córdoba, Spain

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  • Peter M. Brophy

    Affiliation: Institute of Biological, Environmental and Rural Sciences, Aberystwyth University, Aberystwyth, Wales, United Kingdom

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  • Published: May 29, 2012
  • DOI: 10.1371/journal.pntd.0001666

About the Authors

E. James LaCourse, Samirah Perally, Russell M. Morphew, Joseph V. Moxon, Peter M. Brophy
Institute of Biological, Environmental and Rural Sciences, Aberystwyth University, Aberystwyth, Wales, United Kingdom
E. James LaCourse
Molecular and Biochemical Parasitology Group, Liverpool School of Tropical Medicine, Liverpool, England, United Kingdom
Mark Prescott
School of Biological Sciences, University of Liverpool, Liverpool, England, United Kingdom
David J. Dowling, Sandra M. O'Neill
Faculty of Science and Health, Dublin City University, Dublin, Ireland
Anja Kipar, Udo Hetzel
Faculty of Veterinary Science, University of Liverpool, Liverpool, England, United Kingdom
Elizabeth Hoey
School of Biological Sciences, Queen's University of Belfast, Belfast, Northern Ireland, United Kingdom
Rafael Zafra, Leandro Buffoni, José Pérez Arévalo
School of Veterinary Medicine, University of Córdoba, Córdoba, Spain

Corresponding Author

Email: rom@aber.ac.uk

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: EJL PMB. Performed the experiments: EJL SP RMM JVM MP DJD AK UH RZ LB. Analyzed the data: EJL ROM. Contributed reagents/materials/analysis tools: EH. Wrote the paper: EJL RMM JPA SMO PMB.