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Research Article

Clinical Relevance and Discriminatory Value of Elevated Liver Aminotransferase Levels for Dengue Severity

  • Linda K. Lee mail,

    Linda_K_Lee@ttsh.com.sg

    Affiliation: Department of Clinical Epidemiology, Tan Tock Seng Hospital, Singapore, Singapore

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  • Victor C. Gan,

    Affiliation: Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore, Singapore

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  • Vernon J. Lee,

    Affiliations: Department of Clinical Epidemiology, Tan Tock Seng Hospital, Singapore, Singapore, Department of Epidemiology and Public Health, National University of Singapore, Singapore, Singapore

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  • Adriana S. Tan,

    Affiliation: Department of Clinical Epidemiology, Tan Tock Seng Hospital, Singapore, Singapore

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  • Yee Sin Leo,

    Affiliation: Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore, Singapore

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  • David C. Lye

    Affiliations: Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore, Singapore, Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore

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  • Published: June 05, 2012
  • DOI: 10.1371/journal.pntd.0001676

About the Authors

Linda K. Lee, Vernon J. Lee, Adriana S. Tan
Department of Clinical Epidemiology, Tan Tock Seng Hospital, Singapore, Singapore
Victor C. Gan, Yee Sin Leo, David C. Lye
Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore, Singapore
Vernon J. Lee
Department of Epidemiology and Public Health, National University of Singapore, Singapore, Singapore
David C. Lye
Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore

Corresponding Author

Email: Linda_K_Lee@ttsh.com.sg

Competing Interests

YSL is a scientific advisor to Sanofi-Pasteur for a dengue vaccine trial. VJL has received research grants for an unrelated study from GlaxoSmithKline.

Author Contributions

Conceived and designed the experiments: LKL VCG YSL DCL. Performed the experiments: LKL VCG AST. Analyzed the data: LKL VCG. Contributed reagents/materials/analysis tools: VJL AST. Wrote the paper: LKL VCG VJL YSL DCL.