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Research Article

Identification of Mimotopes with Diagnostic Potential for Trypanosoma brucei gambiense Variant Surface Glycoproteins Using Human Antibody Fractions

  • Liesbeth Van Nieuwenhove,

    Affiliation: Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium

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  • Philippe Büscher mail,

    pbuscher@itg.be

    Affiliation: Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium

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  • Fatima Balharbi,

    Affiliation: Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium

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  • Michael Humbert,

    Affiliations: Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Tessa Dieltjens,

    Affiliation: Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium

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  • Yves Guisez,

    Affiliation: Department of Biology, University of Antwerp, Antwerp, Belgium

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  • Veerle Lejon

    Affiliation: Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium

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  • Published: June 12, 2012
  • DOI: 10.1371/journal.pntd.0001682

About the Authors

Liesbeth Van Nieuwenhove, Philippe Büscher, Fatima Balharbi, Tessa Dieltjens, Veerle Lejon
Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium
Michael Humbert
Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America
Michael Humbert
Harvard Medical School, Boston, Massachusetts, United States of America
Yves Guisez
Department of Biology, University of Antwerp, Antwerp, Belgium

Corresponding Author

Email: pbuscher@itg.be

Competing Interests

The results of this study have been the subject matter of a patent application based upon GB1202460.0, filed in the name of Institute of Tropical Medicine.

Author Contributions

Conceived and designed the experiments: LVN FB MH PB VL. Performed the experiments: LVN FB. Analyzed the data: LVN FB PB VL. Contributed reagents/materials/analysis tools: LVN TD YG. Wrote the paper: LVN MH TD YG PB VL.