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Research Article

Molecular Epidemiology of Endemic Human T-Lymphotropic Virus Type 1 in a Rural Community in Guinea-Bissau

  • Carla van Tienen mail,

    c.vantienen@erasmusmc.nl

    Affiliations: Virology, Medical Research Council, Fajara, The Gambia, Medical Microbiology & Infectious Diseases, Erasmus Medical Centre, Rotterdam, The Netherlands

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  • Thushan I. de Silva,

    Affiliations: Virology, Medical Research Council, Fajara, The Gambia, UCL Centre for Medical Molecular Virology, Division of Infection and Immunity, University College London, London, United Kingdom

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  • Luiz Carlos Junior Alcantara,

    Affiliations: Public Health Advanced Laboratory, Gonçalo Moniz Research Center, Oswaldo Cruz Foundation, Salvador, Bahia, Brazil, Bahia School of Medicine and Public Health Foundation for Science Development, Salvador, Bahia, Brazil

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  • Clayton O. Onyango,

    Affiliations: Virology, Medical Research Council, Fajara, The Gambia, KEMRI-Wellcome Trust Programme, Kilifi, Kenya

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  • Sheikh Jarju,

    Affiliation: Virology, Medical Research Council, Fajara, The Gambia

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  • Nato Gonçalves,

    Affiliations: Virology, Medical Research Council, Fajara, The Gambia, Projecto de Saúde de Bandim, Bissau, Guinea-Bissau

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  • Tim Vincent,

    Affiliation: Virology, Medical Research Council, Fajara, The Gambia

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  • Peter Aaby,

    Affiliation: Projecto de Saúde de Bandim, Indepth Network, Bissau, Guinea-Bissau

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  • Hilton Whittle,

    Affiliation: Virology, Medical Research Council, Fajara, The Gambia

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  • Maarten Schim van der Loeff,

    Affiliation: Health Service of Amsterdam (GGD) and Academic Medical Centre, Amsterdam, The Netherlands

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  • Matthew Cotten

    Affiliations: Virology, Medical Research Council, Fajara, The Gambia, Wellcome Trust Genome Campus, Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom

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  • Published: June 12, 2012
  • DOI: 10.1371/journal.pntd.0001690

About the Authors

Carla van Tienen, Thushan I. de Silva, Clayton O. Onyango, Sheikh Jarju, Nato Gonçalves, Tim Vincent, Hilton Whittle, Matthew Cotten
Virology, Medical Research Council, Fajara, The Gambia
Carla van Tienen
Medical Microbiology & Infectious Diseases, Erasmus Medical Centre, Rotterdam, The Netherlands
Thushan I. de Silva
UCL Centre for Medical Molecular Virology, Division of Infection and Immunity, University College London, London, United Kingdom
Luiz Carlos Junior Alcantara
Public Health Advanced Laboratory, Gonçalo Moniz Research Center, Oswaldo Cruz Foundation, Salvador, Bahia, Brazil
Luiz Carlos Junior Alcantara
Bahia School of Medicine and Public Health Foundation for Science Development, Salvador, Bahia, Brazil
Clayton O. Onyango
KEMRI-Wellcome Trust Programme, Kilifi, Kenya
Nato Gonçalves
Projecto de Saúde de Bandim, Bissau, Guinea-Bissau
Peter Aaby
Projecto de Saúde de Bandim, Indepth Network, Bissau, Guinea-Bissau
Maarten Schim van der Loeff
Health Service of Amsterdam (GGD) and Academic Medical Centre, Amsterdam, The Netherlands
Matthew Cotten
Wellcome Trust Genome Campus, Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom

Corresponding Author

Email: c.vantienen@erasmusmc.nl

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MC CvT TIdS MSvdL HW PA. Performed the experiments: CvT TIdS LCJA NG COO SJ. Analyzed the data: CvT MC TIdS LCJA SJ TV. Wrote the paper: CvT MC MSvdL TV. Supervision of data collection and data entry, drafting of the article and critically discussing hypotheses raised by the current study: TV.