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Research Article

Comparison of Schistosoma mansoni Soluble Cercarial Antigens and Soluble Egg Antigens for Serodiagnosing Schistosome Infections

  • Huw Smith †,

    † Deceased.

    Affiliation: Scottish Parasite Diagnostic Reference Laboratory, Department of Bacteriology, Stobhill Hospital, Glasgow, Scotland

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  • Mike Doenhoff mail,

    mike.doenhoff@nottingham.ac.uk

    Affiliation: School of Biology, University of Nottingham, University Park, Nottingham, United Kingdom

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  • Cara Aitken,

    Affiliation: Scottish Parasite Diagnostic Reference Laboratory, Department of Bacteriology, Stobhill Hospital, Glasgow, Scotland

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  • Wendi Bailey,

    Affiliation: Diagnostic Parasitology Laboratory, Liverpool School of Tropical Medicine, Liverpool, United Kingdom

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  • Minjun Ji,

    Affiliation: Department of Pathogen Biology, Nanjing Medical University, Nanjing, China

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  • Emily Dawson,

    Affiliation: School of Biology, University of Nottingham, University Park, Nottingham, United Kingdom

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  • Henk Gilis,

    Affiliation: Parasitology Section, Department of Medical Microbiology, Academic Medical Center, Amsterdam, The Netherlands

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  • Grant Spence,

    Affiliation: Scottish Parasite Diagnostic Reference Laboratory, Department of Bacteriology, Stobhill Hospital, Glasgow, Scotland

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  • Claire Alexander,

    Affiliation: Scottish Parasite Diagnostic Reference Laboratory, Department of Bacteriology, Stobhill Hospital, Glasgow, Scotland

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  • Tom van Gool

    Affiliation: Parasitology Section, Department of Medical Microbiology, Academic Medical Center, Amsterdam, The Netherlands

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  • Published: September 13, 2012
  • DOI: 10.1371/journal.pntd.0001815

About the Authors

Huw Smith, Cara Aitken, Grant Spence, Claire Alexander
Scottish Parasite Diagnostic Reference Laboratory, Department of Bacteriology, Stobhill Hospital, Glasgow, Scotland
Mike Doenhoff, Emily Dawson
School of Biology, University of Nottingham, University Park, Nottingham, United Kingdom
Wendi Bailey
Diagnostic Parasitology Laboratory, Liverpool School of Tropical Medicine, Liverpool, United Kingdom
Minjun Ji
Department of Pathogen Biology, Nanjing Medical University, Nanjing, China
Henk Gilis, Tom van Gool
Parasitology Section, Department of Medical Microbiology, Academic Medical Center, Amsterdam, The Netherlands

Corresponding Author

Email: mike.doenhoff@nottingham.ac.uk

Competing Interests

The S. mansoni-derived antigenic material used in this study was supplied free of charge by BioGlab Ltd, Nottingham, United Kingdom, a company owned by MD.

Author Contributions

Conceived and designed the experiments: M. Doenhoff. Performed the experiments: H. Smith C. Aitken W. Bailey M. Ji H. Gilis G. Spence C. Alexander T. van Gool. Analyzed the data: E. Dawson. Contributed reagents/materials/analysis tools: M. Doenhoff H. Smith C. Aitken W. Bailey H. Gilis G. Spence C. Alexander T. van Gool. Wrote the paper: M. Doenhoff E. Dawson.