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Research Article

Age-Related Patterns in Human Myeloid Dendritic Cell Populations in People Exposed to Schistosoma haematobium Infection

  • Norman Nausch mail,

    nnausch@staffmail.ed.ac.uk

    Affiliation: Institute of Immunology and Infection Research, Centre for Immunity, Infection and Evolution, School of Biological Sciences, Ashworth Laboratories, University of Edinburgh, Edinburgh, United Kingdom

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  • Delphine Louis,

    Affiliations: Institut Curie, Département de Biologie des Tumeurs, Paris, France, Centre d'Investigation Clinique IGR-Curie, CIC-BT-507, Paris, France

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  • Olivier Lantz,

    Affiliations: Institut Curie, Département de Biologie des Tumeurs, Paris, France, Centre d'Investigation Clinique IGR-Curie, CIC-BT-507, Paris, France, Unité Inserm 932, Institut Curie, Paris, France

    X
  • Isabelle Peguillet,

    Affiliations: Institut Curie, Département de Biologie des Tumeurs, Paris, France, Centre d'Investigation Clinique IGR-Curie, CIC-BT-507, Paris, France

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  • François Trottein,

    Affiliation: Center for Infection and Immunity of Lille, Inserm U 1019, CNRS UMR 8204, Université Lille Nord de France, Institut Pasteur de Lille, Lille, France

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  • Isobel Y. D. Chen,

    Affiliation: Institute of Immunology and Infection Research, Centre for Immunity, Infection and Evolution, School of Biological Sciences, Ashworth Laboratories, University of Edinburgh, Edinburgh, United Kingdom

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  • Laura J. Appleby,

    Affiliation: Institute of Immunology and Infection Research, Centre for Immunity, Infection and Evolution, School of Biological Sciences, Ashworth Laboratories, University of Edinburgh, Edinburgh, United Kingdom

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  • Claire D. Bourke,

    Affiliation: Institute of Immunology and Infection Research, Centre for Immunity, Infection and Evolution, School of Biological Sciences, Ashworth Laboratories, University of Edinburgh, Edinburgh, United Kingdom

    Current address: Biology Department, University of York, York, United Kingdom

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  • Nicholas Midzi,

    Affiliation: National Institute of Health Research, Causeway, Harare, Zimbabwe

    Current address: Research Council of Zimbabwe, Harare, Zimbabwe

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  • Takafira Mduluza,

    Affiliation: Department of Biochemistry, University of Zimbabwe, Mount Pleasant, Harare, Zimbabwe

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  • Francisca Mutapi

    Affiliation: Institute of Immunology and Infection Research, Centre for Immunity, Infection and Evolution, School of Biological Sciences, Ashworth Laboratories, University of Edinburgh, Edinburgh, United Kingdom

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  • Published: September 27, 2012
  • DOI: 10.1371/journal.pntd.0001824

About the Authors

Norman Nausch, Isobel Y. D. Chen, Laura J. Appleby, Claire D. Bourke, Francisca Mutapi
Institute of Immunology and Infection Research, Centre for Immunity, Infection and Evolution, School of Biological Sciences, Ashworth Laboratories, University of Edinburgh, Edinburgh, United Kingdom
Delphine Louis, Olivier Lantz, Isabelle Peguillet
Institut Curie, Département de Biologie des Tumeurs, Paris, France
Delphine Louis, Olivier Lantz, Isabelle Peguillet
Centre d'Investigation Clinique IGR-Curie, CIC-BT-507, Paris, France
Olivier Lantz
Unité Inserm 932, Institut Curie, Paris, France
François Trottein
Center for Infection and Immunity of Lille, Inserm U 1019, CNRS UMR 8204, Université Lille Nord de France, Institut Pasteur de Lille, Lille, France
Nicholas Midzi
National Institute of Health Research, Causeway, Harare, Zimbabwe
Takafira Mduluza
Department of Biochemistry, University of Zimbabwe, Mount Pleasant, Harare, Zimbabwe

Corresponding Author

Email: nnausch@staffmail.ed.ac.uk

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: NN OL NM TM FT FM. Performed the experiments: NN DL IP IYDC. Analyzed the data: NN DL OL. Wrote the paper: NN FM LJA CDB. Contributed to field work: LJA CDB. Contributed to final version of the manuscript: LJA CDB OL FT.