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Research Article

Dramatic Increase in Glycerol Biosynthesis upon Oxidative Stress in the Anaerobic Protozoan Parasite Entamoeba histolytica

  • Afzal Husain,

    Affiliations: Department of Parasitology, National Institute of Infectious Diseases, Tokyo, Japan, Department of Parasitology, Gunma University Graduate School of Medicine, Maebashi, Japan

    Current address: Department of Immunology and Genomic Medicine, Graduate School of Medicine, Kyoto University Kyoto, Japan

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  • Dan Sato,

    Affiliation: Institute for Advanced Biosciences, Keio University, Tsuruoka, Japan

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  • Ghulam Jeelani,

    Affiliations: Department of Parasitology, National Institute of Infectious Diseases, Tokyo, Japan, Department of Biochemistry and Integrative Medical Biology, School of Medicine, Keio University, Tokyo, Japan

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  • Tomoyoshi Soga,

    Affiliation: Institute for Advanced Biosciences, Keio University, Tsuruoka, Japan

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  • Tomoyoshi Nozaki mail

    nozaki@nih.go.jp

    Affiliations: Department of Parasitology, National Institute of Infectious Diseases, Tokyo, Japan, Graduate School of Life and Environmental Sciences, University of Tsukuba, Tsukuba, Japan

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  • Published: September 27, 2012
  • DOI: 10.1371/journal.pntd.0001831

About the Authors

Afzal Husain, Ghulam Jeelani, Tomoyoshi Nozaki
Department of Parasitology, National Institute of Infectious Diseases, Tokyo, Japan
Afzal Husain
Department of Parasitology, Gunma University Graduate School of Medicine, Maebashi, Japan
Dan Sato, Tomoyoshi Soga
Institute for Advanced Biosciences, Keio University, Tsuruoka, Japan
Ghulam Jeelani
Department of Biochemistry and Integrative Medical Biology, School of Medicine, Keio University, Tokyo, Japan
Tomoyoshi Nozaki
Graduate School of Life and Environmental Sciences, University of Tsukuba, Tsukuba, Japan

Corresponding Author

Email: nozaki@nih.go.jp

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AH DS GJ TN. Performed the experiments: AH DS GJ. Analyzed the data: AH DS GJ. Contributed reagents/materials/analysis tools: TS TN. Wrote the paper: AH TN.