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Research Article

Serine Protease(s) Secreted by the Nematode Trichuris muris Degrade the Mucus Barrier

  • Sumaira Z. Hasnain mail,

    shasnain@mmri.mater.org.au (SZH); dave.thornton@manchester.ac.uk (DJT)

    Affiliations: Immunity, Infection and Inflammation, Mater Medical Research Institute, Brisbane, Australia, Manchester Immunology Group, Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom, Wellcome Trust Centre for Cell-Matrix Research, Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom

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  • Michael A. McGuckin,

    Affiliation: Immunity, Infection and Inflammation, Mater Medical Research Institute, Brisbane, Australia

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  • Richard K. Grencis,

    Affiliation: Manchester Immunology Group, Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom

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  • David J. Thornton mail

    shasnain@mmri.mater.org.au (SZH); dave.thornton@manchester.ac.uk (DJT)

    Affiliation: Wellcome Trust Centre for Cell-Matrix Research, Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom

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  • Published: October 11, 2012
  • DOI: 10.1371/journal.pntd.0001856

About the Authors

Sumaira Z. Hasnain, Michael A. McGuckin
Immunity, Infection and Inflammation, Mater Medical Research Institute, Brisbane, Australia
Sumaira Z. Hasnain, Richard K. Grencis
Manchester Immunology Group, Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom
Sumaira Z. Hasnain, David J. Thornton
Wellcome Trust Centre for Cell-Matrix Research, Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SZH MAM RKG DJT. Performed the experiments: SZH. Analyzed the data: SZH. Wrote the paper: SZH. Critical revision of manuscript: MAM DJT RKG.