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Research Article

Mechanistic and Single-Dose In Vivo Therapeutic Studies of Cry5B Anthelmintic Action against Hookworms

  • Yan Hu equal contributor,

    equal contributor Contributed equally to this work with: Yan Hu, Bin Zhan

    Affiliation: Section of Cell and Developmental Biology, University of California San Diego, La Jolla, California, United States of America

    X
  • Bin Zhan equal contributor mail,

    equal contributor Contributed equally to this work with: Yan Hu, Bin Zhan

    bzhan@bcm.edu (YH); raroian@ucsd.edu (RVA)

    Affiliation: Section of Tropical Medicine, Department of Pediatrics, Baylor College of Medicine, Houston, Texas, United States of America

    X
  • Brian Keegan,

    Affiliation: Section of Tropical Medicine, Department of Pediatrics, Baylor College of Medicine, Houston, Texas, United States of America

    X
  • Ying Y. Yiu,

    Affiliation: Section of Cell and Developmental Biology, University of California San Diego, La Jolla, California, United States of America

    X
  • Melanie M. Miller,

    Affiliation: Section of Cell and Developmental Biology, University of California San Diego, La Jolla, California, United States of America

    X
  • Kathryn Jones,

    Affiliation: Section of Tropical Medicine, Department of Pediatrics, Baylor College of Medicine, Houston, Texas, United States of America

    X
  • Raffi V. Aroian mail

    bzhan@bcm.edu (YH); raroian@ucsd.edu (RVA)

    Affiliation: Section of Cell and Developmental Biology, University of California San Diego, La Jolla, California, United States of America

    X
  • Published: November 08, 2012
  • DOI: 10.1371/journal.pntd.0001900

About the Authors

Yan Hu, Ying Y. Yiu, Melanie M. Miller, Raffi V. Aroian
Section of Cell and Developmental Biology, University of California San Diego, La Jolla, California, United States of America
Bin Zhan, Brian Keegan, Kathryn Jones
Section of Tropical Medicine, Department of Pediatrics, Baylor College of Medicine, Houston, Texas, United States of America

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: YH BZ RVA. Performed the experiments: YH BZ BK YYY MMM KJ. Analyzed the data: YH BZ RVA. Wrote the paper: RVA.