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Research Article

Administration of E2 and NS1 siRNAs Inhibit Chikungunya Virus Replication In Vitro and Protects Mice Infected with the Virus

  • Deepti Parashar,

    Affiliation: National Institute of Virology, Microbial Containment Complex, Sus Road, Pashan, Pune, India

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  • Mandar S. Paingankar,

    Affiliation: National Institute of Virology, Microbial Containment Complex, Sus Road, Pashan, Pune, India

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  • Satyendra Kumar,

    Affiliation: National Institute of Virology, Microbial Containment Complex, Sus Road, Pashan, Pune, India

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  • Mangesh D. Gokhale,

    Affiliation: National Institute of Virology, Microbial Containment Complex, Sus Road, Pashan, Pune, India

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  • A. B. Sudeep,

    Affiliation: National Institute of Virology, Microbial Containment Complex, Sus Road, Pashan, Pune, India

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  • Sapana B. Shinde,

    Affiliation: National Institute of Virology, Microbial Containment Complex, Sus Road, Pashan, Pune, India

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  • V. A. Arankalle mail

    varankalle@yahoo.com

    Affiliation: National Institute of Virology, Microbial Containment Complex, Sus Road, Pashan, Pune, India

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  • Published: September 05, 2013
  • DOI: 10.1371/journal.pntd.0002405

About the Authors

Deepti Parashar, Mandar S. Paingankar, Satyendra Kumar, Mangesh D. Gokhale, A. B. Sudeep, Sapana B. Shinde, V. A. Arankalle
National Institute of Virology, Microbial Containment Complex, Sus Road, Pashan, Pune, India

Corresponding Author

Email: varankalle@yahoo.com

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DP MSP VAA. Performed the experiments: DP MSP SK MDG ABS SBS. Analyzed the data: MSP. Contributed reagents/materials/analysis tools: DP MSP SK MDG ABS SBS VAA. Wrote the paper: DP MSP VAA.