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Research Article

Prevention of Tungiasis and Tungiasis-Associated Morbidity Using the Plant-Based Repellent Zanzarin: A Randomized, Controlled Field Study in Rural Madagascar

  • Marlene Thielecke,

    Affiliation: Institute of Microbiology and Hygiene, Campus Benjamin Franklin, Charité University Medicine, Berlin, Germany

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  • Vaomalala Raharimanga,

    Affiliation: Institut Pasteur de Madagascar, Antananarivo, Madagascar

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  • Christophe Rogier,

    Affiliation: Institut Pasteur de Madagascar, Antananarivo, Madagascar

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  • Manuela Stauss-Grabo,

    Affiliation: Faculty of Medicine, Mainz University, Mainz, Germany

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  • Vincent Richard,

    Affiliation: Institut Pasteur de Madagascar, Antananarivo, Madagascar

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  • Hermann Feldmeier mail

    hermann.feldmeier@charite.de

    Affiliation: Institute of Microbiology and Hygiene, Campus Benjamin Franklin, Charité University Medicine, Berlin, Germany

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  • Published: September 19, 2013
  • DOI: 10.1371/journal.pntd.0002426

About the Authors

Marlene Thielecke, Hermann Feldmeier
Institute of Microbiology and Hygiene, Campus Benjamin Franklin, Charité University Medicine, Berlin, Germany
Vaomalala Raharimanga, Christophe Rogier, Vincent Richard
Institut Pasteur de Madagascar, Antananarivo, Madagascar
Manuela Stauss-Grabo
Faculty of Medicine, Mainz University, Mainz, Germany

Corresponding Author

Email: hermann.feldmeier@charite.de

Competing Interests

Dr. Feldmeier acknowledges the receipt of consulting fees and travel grants from Engelhard Arzneimittel GmbH & Co. KG. Dr. Stauss-Grabo was an employee of Engelhard Arzneimittel GmbH & Co. KG at the time the study was planned. This does not alter our adherence to all PLOS policies on sharing data and materials. The other authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: HF CR MSG. Performed the experiments: MT VRa. Analyzed the data: MT HF CR. Contributed reagents/materials/analysis tools: VRi CR MSG. Wrote the paper: MT HF. Critical revision of the manuscript for important intellectual content: HF CR MSG MT VRa VRi.