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Research Article

Local Immune Responses of the Chinese Water Buffalo, Bubalus bubalis, against Schistosoma japonicum Larvae: Crucial Insights for Vaccine Design

  • Hamish E. G. McWilliam mail,

    hamish.mcwilliam@monash.edu

    Affiliations: Biotechnology Research Laboratories, School of Biomedical Sciences, Monash University, Melbourne, Victoria, Australia, Australian Research Council Centre of Excellence in Structural and Functional Microbial Genomics, Monash University, Melbourne, Victoria, Australia

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  • David Piedrafita,

    Affiliations: Biotechnology Research Laboratories, School of Biomedical Sciences, Monash University, Melbourne, Victoria, Australia, Australian Research Council Centre of Excellence in Structural and Functional Microbial Genomics, Monash University, Melbourne, Victoria, Australia

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  • Yuesheng Li,

    Affiliations: Hunan Institute of Parasitic Diseases, Yueyang, Hunan, China, Molecular Parasitology Laboratory, Queensland Institute of Medical Research, Brisbane, Queensland, Australia

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  • Mao Zheng,

    Affiliation: Hunan Institute of Parasitic Diseases, Yueyang, Hunan, China

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  • Yongkang He,

    Affiliation: Hunan Institute of Parasitic Diseases, Yueyang, Hunan, China

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  • Xinling Yu,

    Affiliation: Hunan Institute of Parasitic Diseases, Yueyang, Hunan, China

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  • Donald P. McManus,

    Affiliation: Molecular Parasitology Laboratory, Queensland Institute of Medical Research, Brisbane, Queensland, Australia

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  • Els N. T. Meeusen

    Affiliations: Biotechnology Research Laboratories, School of Biomedical Sciences, Monash University, Melbourne, Victoria, Australia, Australian Research Council Centre of Excellence in Structural and Functional Microbial Genomics, Monash University, Melbourne, Victoria, Australia

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  • Published: September 26, 2013
  • DOI: 10.1371/journal.pntd.0002460

About the Authors

Hamish E. G. McWilliam, David Piedrafita, Els N. T. Meeusen
Biotechnology Research Laboratories, School of Biomedical Sciences, Monash University, Melbourne, Victoria, Australia
Hamish E. G. McWilliam, David Piedrafita, Els N. T. Meeusen
Australian Research Council Centre of Excellence in Structural and Functional Microbial Genomics, Monash University, Melbourne, Victoria, Australia
Yuesheng Li, Mao Zheng, Yongkang He, Xinling Yu
Hunan Institute of Parasitic Diseases, Yueyang, Hunan, China
Yuesheng Li, Donald P. McManus
Molecular Parasitology Laboratory, Queensland Institute of Medical Research, Brisbane, Queensland, Australia

Corresponding Author

Email: hamish.mcwilliam@monash.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: HEGM DP YL DPM ENTM. Performed the experiments: HEGM DP MZ YH XY ENTM. Analyzed the data: HEGM DP ENTM. Wrote the paper: HEGM DP ENTM DPM.