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Research Article

Responses of Murine and Human Macrophages to Leptospiral Infection: A Study Using Comparative Array Analysis

  • Feng Xue equal contributor mail,

    equal contributor Contributed equally to this work with: Feng Xue, Xinghui Zhao

    fong.hsueh@gmail.com

    Affiliations: Beijing Friendship Hospital, Capital Medical University, Beijing, China, Beijing Tropical Medicine Research Institute, Beijing, China, Beijing Key Laboratory for Research on Prevention and Treatment of Tropical Diseases, Beijing, China, Beijing Institute of Biotechnology, Beijing, China

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  • Xinghui Zhao equal contributor,

    equal contributor Contributed equally to this work with: Feng Xue, Xinghui Zhao

    Affiliation: Beijing Institute of Biotechnology, Beijing, China

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  • Yingchao Yang,

    Affiliation: Division of Parasitic Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control, Beijing, China

    X
  • Jinping Zhao,

    Affiliation: School of Life Sciences, Tsinghua University, Beijing, China

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  • Yutao Yang,

    Affiliations: Department of Neurobiology, Capital Medical University, Beijing, China, Beijing Key Laboratory of Major Brain Disorders, Beijing Institute of Brain Disorders, Beijing, China

    X
  • Yongguo Cao,

    Affiliation: College of Veterinary Medicine, Jilin University, Changchun, China

    X
  • Cailing Hong,

    Affiliation: Beijing Friendship Hospital, Capital Medical University, Beijing, China

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  • Yuan Liu,

    Affiliation: Beijing Friendship Hospital, Capital Medical University, Beijing, China

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  • Lan Sun,

    Affiliations: Beijing Friendship Hospital, Capital Medical University, Beijing, China, Beijing Tropical Medicine Research Institute, Beijing, China, Beijing Key Laboratory for Research on Prevention and Treatment of Tropical Diseases, Beijing, China

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  • Minjun Huang,

    Affiliations: Beijing Friendship Hospital, Capital Medical University, Beijing, China, Beijing Tropical Medicine Research Institute, Beijing, China, Beijing Key Laboratory for Research on Prevention and Treatment of Tropical Diseases, Beijing, China

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  • Junchao Gu

    Affiliations: Beijing Friendship Hospital, Capital Medical University, Beijing, China, Beijing Tropical Medicine Research Institute, Beijing, China, Beijing Key Laboratory for Research on Prevention and Treatment of Tropical Diseases, Beijing, China

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  • Published: October 10, 2013
  • DOI: 10.1371/journal.pntd.0002477

About the Authors

Feng Xue, Cailing Hong, Yuan Liu, Lan Sun, Minjun Huang, Junchao Gu
Beijing Friendship Hospital, Capital Medical University, Beijing, China
Feng Xue, Lan Sun, Minjun Huang, Junchao Gu
Beijing Tropical Medicine Research Institute, Beijing, China
Feng Xue, Lan Sun, Minjun Huang, Junchao Gu
Beijing Key Laboratory for Research on Prevention and Treatment of Tropical Diseases, Beijing, China
Feng Xue, Xinghui Zhao
Beijing Institute of Biotechnology, Beijing, China
Yingchao Yang
Division of Parasitic Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control, Beijing, China
Jinping Zhao
School of Life Sciences, Tsinghua University, Beijing, China
Yutao Yang
Department of Neurobiology, Capital Medical University, Beijing, China
Yutao Yang
Beijing Key Laboratory of Major Brain Disorders, Beijing Institute of Brain Disorders, Beijing, China
Yongguo Cao
College of Veterinary Medicine, Jilin University, Changchun, China

Corresponding Author

Email: fong.hsueh@gmail.com

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: FX. Performed the experiments: FX XZ JZ YiY YuY YC CH YL LS MH. Analyzed the data: FX XZ JZ JG. Contributed reagents/materials/analysis tools: FX JZ YiY YuY YC MH JG. Wrote the paper: FX.