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Research Article

Effect of Maternal Schistosoma mansoni Infection and Praziquantel Treatment During Pregnancy on Schistosoma mansoni Infection and Immune Responsiveness among Offspring at Age Five Years

  • Robert Tweyongyere mail,

    tmrobert966@gmail.com

    Affiliations: Department of Veterinary Pharmacy, Clinical and Comparative Medicine, Makerere University, Kampala, Uganda, Uganda Virus Research Institute, Entebbe, Uganda

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  • Peter Naniima,

    Affiliation: Uganda Virus Research Institute, Entebbe, Uganda

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  • Patrice A. Mawa,

    Affiliation: Uganda Virus Research Institute, Entebbe, Uganda

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  • Frances M. Jones,

    Affiliation: Department of Pathology, Cambridge University, Cambridge, United Kingdom

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  • Emily L. Webb,

    Affiliation: London School of Hygiene and Tropical Medicine, London, United Kingdom

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  • Stephen Cose,

    Affiliations: Uganda Virus Research Institute, Entebbe, Uganda, London School of Hygiene and Tropical Medicine, London, United Kingdom

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  • David W. Dunne,

    Affiliation: Department of Pathology, Cambridge University, Cambridge, United Kingdom

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  • Alison M. Elliott

    Affiliations: Uganda Virus Research Institute, Entebbe, Uganda, London School of Hygiene and Tropical Medicine, London, United Kingdom

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  • Published: October 17, 2013
  • DOI: 10.1371/journal.pntd.0002501

About the Authors

Robert Tweyongyere
Department of Veterinary Pharmacy, Clinical and Comparative Medicine, Makerere University, Kampala, Uganda
Robert Tweyongyere, Peter Naniima, Patrice A. Mawa, Stephen Cose, Alison M. Elliott
Uganda Virus Research Institute, Entebbe, Uganda
Frances M. Jones, David W. Dunne
Department of Pathology, Cambridge University, Cambridge, United Kingdom
Emily L. Webb, Stephen Cose, Alison M. Elliott
London School of Hygiene and Tropical Medicine, London, United Kingdom

Corresponding Author

Email: tmrobert966@gmail.com

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: RT AME DWD. Performed the experiments: RT PN PAM FMJ . Analyzed the data: RT ELW AME. Contributed reagents/materials/analysis tools: RT AME DWD. Wrote the paper: RT AME DWD SC.