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Research Article

Over-Expression of 60s Ribosomal L23a Is Associated with Cellular Proliferation in SAG Resistant Clinical Isolates of Leishmania donovani

  • Sanchita Das,

    Affiliation: Division of Parasitology, CSIR-Central Drug Research Institute, Lucknow, India

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  • Priyanka Shah,

    Affiliation: Molecular and Structural Biology, CSIR-Central Drug Research Institute, Lucknow, India

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  • Rajendra K. Baharia,

    Affiliation: Division of Parasitology, CSIR-Central Drug Research Institute, Lucknow, India

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  • Rati Tandon,

    Affiliation: Division of Parasitology, CSIR-Central Drug Research Institute, Lucknow, India

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  • Prashant Khare,

    Affiliation: Division of Parasitology, CSIR-Central Drug Research Institute, Lucknow, India

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  • Shyam Sundar,

    Affiliation: Department of Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India

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  • Amogh A. Sahasrabuddhe,

    Affiliation: Molecular and Structural Biology, CSIR-Central Drug Research Institute, Lucknow, India

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  • M. I. Siddiqi,

    Affiliation: Molecular and Structural Biology, CSIR-Central Drug Research Institute, Lucknow, India

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  • Anuradha Dube mail

    anuradha_dube@hotmail.com, anuradha_dube@rediffmail.com

    Affiliation: Division of Parasitology, CSIR-Central Drug Research Institute, Lucknow, India

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  • Published: December 05, 2013
  • DOI: 10.1371/journal.pntd.0002527

About the Authors

Sanchita Das, Rajendra K. Baharia, Rati Tandon, Prashant Khare, Anuradha Dube
Division of Parasitology, CSIR-Central Drug Research Institute, Lucknow, India
Priyanka Shah, Amogh A. Sahasrabuddhe, M. I. Siddiqi
Molecular and Structural Biology, CSIR-Central Drug Research Institute, Lucknow, India
Shyam Sundar
Department of Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SD AAS MIS AD. Performed the experiments: SD PS RKB RT PK. Analyzed the data: SD AAS MIS AD. Contributed reagents/materials/analysis tools: AAS SS MIS AD. Wrote the paper: SD PS AAS MIS AD. Obtained permission for use of pXG-'GFP vector: AAS.