Advertisement
Research Article

Rapid, Serial, Non-invasive Assessment of Drug Efficacy in Mice with Autoluminescent Mycobacterium ulcerans Infection

  • Tianyu Zhang,

    Affiliations: Center for Tuberculosis Research, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, State Key Laboratory of Respiratory Diseases, Center for Infection and Immunity, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, Guangdong, the People's Republic of China

    X
  • Si-Yang Li,

    Affiliation: Center for Tuberculosis Research, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

    X
  • Paul J. Converse,

    Affiliation: Center for Tuberculosis Research, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

    X
  • Jacques H. Grosset,

    Affiliation: Center for Tuberculosis Research, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

    X
  • Eric L. Nuermberger mail

    enuermb@jhmi.edu

    Affiliations: Center for Tuberculosis Research, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America

    X
  • Published: December 19, 2013
  • DOI: 10.1371/journal.pntd.0002598

About the Authors

Tianyu Zhang, Si-Yang Li, Paul J. Converse, Jacques H. Grosset, Eric L. Nuermberger
Center for Tuberculosis Research, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
Tianyu Zhang
State Key Laboratory of Respiratory Diseases, Center for Infection and Immunity, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, Guangdong, the People's Republic of China
Eric L. Nuermberger
Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America

Corresponding Author

Email: enuermb@jhmi.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: ELN TZ. Performed the experiments: TZ SYL. Analyzed the data: TZ ELN PJC JHG. Contributed reagents/materials/analysis tools: TZ PJC ELN. Wrote the paper: TZ ELN PJC JHG.